UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T24C2.5	T24C2.5	7e-59	chrX 14,538,539	contains similarity to Homo sapiens Nuclear receptor co-repressor 1; ENSEMBL:ENSP00000268712
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	R09D1.10	R09D1.10	n/a	chrII 9,465,285	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
4	ZK228.1	ZK228.1	n/a	chrV 18,445,683	contains similarity to Mus musculus SOX-13 protein.; SW:SX13_MOUSE
5	srx-86	F38B7.7	n/a	chrV 11,563,703	C. elegans SRX-86 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
7	pme-2	E02H1.4	n/a	chrII 9,594,003	pme-2 encodes a poly(ADP-ribose) polymerase (PARP) orthologous to human PARP2 (OMIM:607725); PME-2 has a predicted C-terminal catalytic domain; PME-2 has PARP activity in vitro, which is blocked by mammalian PARP inhibitors; since these inhibitors also cause embryonic lethality in worms exposed to ionizing radiation, PME-1 is likely to be required in vivo for repairing broken DNA.
8	nlp-16	T13A10.5	n/a	chrIV 6,257,461	nlp-16 encodes a predicted neuropeptide that does not belong to a multigene family in C. elegans and is not clearly related to well-characterized neuropeptides; the peptide encoded by nlp-16 has been isolated from Ascaris suum.
9	F26E4.5	F26E4.5	n/a	chrI 9,769,984	F26E4.5 encodes an SH2 domain-containing tyrosine kinase related to the vertebrate FER non-receptor protein tyrosine kinase; loss of F26E4.5 activity in an RNAi-hypersensitive strain results in axon guidance defects indicating that F26E4.5 likely plays a role in regulation of axon navigation.
10	C44C10.3	C44C10.3	n/a	chrX 11,703,337	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
11	T11F8.2	T11F8.2	n/a	chrIV 5,477,982
12	ZK1053.6	ZK1053.6	n/a	chrI 13,239,621	ZK1053.6 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK1053.6 is predicted to transport Mg(2+) into cells; ZK1053.6 is paralogous to K07H8.2 and ZK185.2, and has no obvious function in mass RNAi assays.
13	clec-212	F19F10.7	n/a	chrV 7,566,626	C. elegans CLEC-212 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
14	btb-16	F39E9.2	n/a	chrII 3,297,442	C. elegans BTB-16 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
15	C41D11.3	C41D11.3	n/a	chrI 4,430,732	contains similarity to Interpro domain IPR001041 (Ferredoxin)
16	ZK682.7	ZK682.7	n/a	chrV 9,291,373
17	Y40H7A.9	Y40H7A.9	n/a	chrIV 15,207,561	contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
18	Y76A2B.5	Y76A2B.5	n/a	chrIII 13,547,827	contains similarity to Danio rerio Zgc:91819 protein.; TR:Q6GMH4
19	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
20	C50B8.3	C50B8.3	n/a	chrV 13,567,762	contains similarity to Pfam domain PF08547 Complex I intermediate-associated protein 30 (CIA30) contains similarity to Interpro domain IPR013857 (NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30)
21	M4.1	M4.1	n/a	chrIV 3,215,716	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR009053 (Prefoldin), IPR000253 (Forkhead-associated)
22	cpsf-2	F09G2.4	n/a	chrV 7,181,006	C. elegans CPSF-2 protein; contains similarity to Pfam domains PF00753 (Metallo-beta-lactamase superfamily) , PF07521 (RNA-metabolising metallo-beta-lactamase) contains similarity to Interpro domains IPR011108 (RNA-metabolising metallo-beta-lactamase), IPR001279 (Beta-lactamase-like)
23	F20E11.7	F20E11.7	n/a	chrV 17,465,622	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domains IPR005098 (Protein of unknown function DUF281), IPR006662 (Thioredoxin-related)
24	Y38H6A.2	Y38H6A.2	n/a	chrV 20,325,833	contains similarity to Chlamydia pneumoniae Hypothetical protein CPn0168.; TR:Q9Z916
25	C39E6.2	C39E6.2	n/a	chrX 4,754,889
26	zig-7	F54D7.4	n/a	chrI 4,791,457	zig-7 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; loss of zig-7 activity via RNAi has been reported to result in aldicarb resistance; a zig-7::gfp reporter fusion is expressed in body wall muscle.
27	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
28	F53G2.2	F53G2.2	n/a	chrII 2,483,921
29	nuc-1	C07B5.5	n/a	chrX 9,541,102	The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding; during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment.
30	Y39F10A.2	Y39F10A.2	n/a	chrII 780,543	contains similarity to Pfam domain PF06079 Apyrase contains similarity to Interpro domain IPR009283 (Apyrase)
31	C10A4.5	C10A4.5	n/a	chrX 7,394,900
32	ceh-27	F46F3.1	n/a	chrV 11,663,161	ceh-27 encodes a homeodomain protein of the NK-2 class that contains Drosophila scarecrow and human NKX-2 (OMIM:606727); CEH-27 activity is essential for embryogenesis and appears to be required for maintaining hypodermal integrity during movement as embryos lacking CEH-27 burst at a breach in the ventral hypodermis upon commencement of muscle contractions; CEH-27 expression is first detected in the ~100-cell embryo in what appear to be MS-derived cells while in later embryos expression is seen in a number of cells in the anterior head region.
33	M02A10.1	M02A10.1	n/a	chrX 707,178
34	D2024.2	D2024.2	n/a	chrIV 7,244,813	contains similarity to Mus musculus Probable arylformamidase (EC 3.5.1.9) (Kynurenine formamidase) (KF).; SW:Q8K4H1
35	Y12A6A.1	Y12A6A.1	n/a	chrX 13,620,760
36	sre-32	W05H5.7	n/a	chrII 12,455,773	C. elegans SRE-32 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000293 (Channel forming colicin, C-terminal cytotoxic)
37	btb-4	F59H6.12	n/a	chrII 2,032,856	C. elegans BTB-4 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
38	nhr-218	T13F3.2	n/a	chrV 16,259,537	C. elegans NHR-218 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	M02F4.2	M02F4.2	n/a	chrX 3,033,806
40	dsc-1	C18B12.3	n/a	chrX 15,032,922	C. elegans DSC-1 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
41	W09D6.5	W09D6.5	n/a	chrIII 11,089,923	contains similarity to Saccharomyces cerevisiae cell wall integrity and stress response component 1; SGD:YOR008C
42	srh-190	C17E7.2	n/a	chrV 3,903,811	C. elegans SRH-190 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	let-70	M7.1	n/a	chrIV 11,081,640	let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system.
44	clec-44	R07C3.12	n/a	chrII 921,144	C. elegans CLEC-44 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
45	clec-40	T20B3.13	n/a	chrV 16,840,047	C. elegans CLEC-40 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	str-166	T08B6.6	n/a	chrIV 4,885,569	C. elegans STR-166 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	F19G12.4	F19G12.4	n/a	chrX 1,417,386
48	str-108	F10A3.13	n/a	chrV 16,166,795	C. elegans STR-108 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	Y37D8A.21	Y37D8A.21	n/a	chrIII 12,929,839	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
50	grsp-3	C34D4.11	n/a	chrIV 7,131,263	C. elegans GRSP-3 protein; contains similarity to Interpro domains IPR005405 (Potassium channel, voltage dependent, Kv3.4), IPR002952 (Eggshell protein), IPR003991 (Pertactin virulence factor, C-terminal), IPR000817 (Prion protein), IPR001951 (Histone H4)