UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T27A1.2	T27A1.2	5.9999999999999995e-174	chrII 532,038	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
2	C10B5.1	C10B5.1	n/a	chrV 8,582,501	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR016160 (Aldehyde dehydrogenase, conserved site), IPR015943 (WD40/YVTN repeat-like)
3	ncx-3	ZC168.1	n/a	chrIV 10,719,177	ncx-3 encodes a putative 3Na[+]/1Ca[2+] exchanger, orthologous to human SLC8A1-3 and paralogous to NCX-1/-2; NCX-3 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-3 has tandem Calx-alpha and Calx-beta domains predicted to carry out ion transport and regulation; NCX-3 has no obvious function in mass RNAi assays.
4	ZK666.4	ZK666.4	n/a	chrII 10,477,397	contains similarity to Oryza sativa Putative retinoblastoma-related protein 1.; TR:Q84QM3
5	wee-1.1	F35H8.7	n/a	chrII 9,582,677	C. elegans WEE-1.1 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	srx-93	F59B1.3	n/a	chrV 3,620,070	C. elegans SRX-93 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR001411 (Tetracycline resistance protein, TetB)
7	str-229	C17E7.11	n/a	chrV 3,901,512	C. elegans STR-229 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	M151.3	M151.3	n/a	chrII 3,629,023	contains similarity to Homo sapiens Isoform 2 of Girdin; ENSEMBL:ENSP00000263630
9	F10D2.8	F10D2.8	n/a	chrV 7,150,438	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
10	T23G5.3	T23G5.3	n/a	chrIII 9,230,130	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF00786 (P21-Rho-binding domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000095 (PAK-box/P21-Rho-binding), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
11	set-13	K12H6.11	n/a	chrII 2,818,048	set-13 encodes a SET domain-containing protein; SET-13 has no non-nematode orthologs, but several paralogs (SET-6, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-13(n5012) nor set-13(RNAi) have any obvious phenotypes.
12	Y73C8C.3	Y73C8C.3	n/a	chrV 3,116,714	contains similarity to Homo sapiens Isoform 3 of Centromeric protein E; ENSEMBL:ENSP00000369365
13	M01E11.1	M01E11.1	n/a	chrI 5,582,772	contains similarity to Pfam domain PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family contains similarity to Interpro domain IPR007269 (Isoprenylcysteine carboxyl methyltransferase)
14	F26D2.14	F26D2.14	n/a	chrV 16,436,268	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
15	C08H9.7	C08H9.7	n/a	chrII 9,860,547	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
16	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
17	C48B4.7	C48B4.7	n/a	chrIII 9,558,981	contains similarity to Xenopus laevis Hypothetical protein.; TR:Q7ZYB3
18	ZC477.4	ZC477.4	n/a	chrIV 7,098,647
19	F47B7.3	F47B7.3	n/a	chrX 3,763,711	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
20	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
21	F10A3.1	F10A3.1	n/a	chrV 16,140,754	F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
22	hlh-26	C17C3.8	n/a	chrII 5,533,262	C. elegans HLH-26 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
23	lam-3	T22A3.8	n/a	chrI 10,614,936	lam-3 is orthologous to human LAMININ ALPHA-2 (LAMA2; OMIM:156225), which when mutated leads to merosin-deficient congenital muscular dystrophy.
24	F13B9.6	F13B9.6	n/a	chrX 8,266,671	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
25	Y116A8C.20	Y116A8C.20	n/a	chrIV 17,041,175	Y116A8C.20 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y116A8C.20 is predicted to function as an RNA-binding protein.
26	srh-52	R08H2.7	n/a	chrV 15,375,587	C. elegans SRH-52 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	T05B4.8	T05B4.8	n/a	chrV 4,115,949	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
28	srbc-32	C02A12.5	n/a	chrV 3,486,251	C. elegans SRBC-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
29	M04D8.4	M04D8.4	n/a	chrIII 10,030,454	contains similarity to Clostridium perfringens Hypothetical protein CPE0262.; TR:Q8XNS0
30	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
31	rfc-2	F58F6.4	n/a	chrIV 1,350,136	rfc-2 encodes a member of the AAA family that are ATPases associated with DNA replication and has highest similarity to the mouse Replication factor C 40 kDa subunit, and affects embryonic viability, fertility, and locomotion in a large-scale RNAi screen.
32	C41D7.1	C41D7.1	n/a	chrII 357,032
33	T26A5.4	T26A5.4	n/a	chrIII 6,461,112	contains similarity to Pfam domain PF00534 Glycosyl transferases group 1 contains similarity to Interpro domain IPR001296 (Glycosyl transferase, group 1)
34	F36H5.4	F36H5.4	n/a	chrII 1,762,375
35	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
36	srx-41	F59B1.7	n/a	chrV 3,635,917	C. elegans SRX-41 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000276 (GPCR, rhodopsin-like)
37	Y40B1B.7	Y40B1B.7	n/a	chrI 13,427,466	contains similarity to Rattus norvegicus Coiled-coil domain-containing protein 86 (Cytokine-induced proteinswith coiled-coil domain).; SW:Q5XIB5
38	nhr-185	F47C10.1	n/a	chrV 3,845,862	C. elegans NHR-185 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000306 (Zinc finger, FYVE-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	ZC477.7	ZC477.7	n/a	chrIV 7,110,897
40	W06G6.12	W06G6.12	n/a	chrV 16,652,565	contains similarity to Methanosarcina mazei Hypothetical protein MM2681.; TR:Q8PTN2
41	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
42	bath-34	W02A11.5	n/a	chrI 12,751,040	C. elegans BATH-34 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
44	R11A5.3	R11A5.3	n/a	chrI 7,863,191	contains similarity to Mycobacterium tuberculosis DNA-binding protein HU homolog (Histone-like protein) (Hlp) (21-kDaslaminin-2-binding protein).; SW:DBH_MYCTU
45	srh-184	D1054.12	n/a	chrV 10,797,485	C. elegans SRH-184 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
47	F41C6.2	F41C6.2	n/a	chrX 6,870,966
48	T05A12.3	T05A12.3	n/a	chrIV 6,885,597	contains similarity to Cryptosporidium parvum Iowa II Large low complexity coiled coil protien with large repeat region.; TR:Q5CQL9
49	T18D3.1	T18D3.1	n/a	chrX 12,456,267	contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
50	Y39A1A.2	Y39A1A.2	n/a	chrIII 10,602,626	contains similarity to Oryza sativa Hypothetical protein.; TR:Q9LH25