UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srt-47	Y41E3.12	0	chrIV 15,051,352	C. elegans SRT-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR006121 (Heavy metal transport/detoxification protein)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	scl-8	C39E9.6	n/a	chrIV 13,072,085	C. elegans SCL-8 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
4	T19D2.3	T19D2.3	n/a	chrX 3,939,726
5	T08G3.6	T08G3.6	n/a	chrV 16,446,543	contains similarity to Interpro domain IPR008975 ()
6	srt-12	E03D2.4	2e-21	chrV 4,241,727	C. elegans SRT-12 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
7	F46B3.1	F46B3.1	n/a	chrV 20,592,082	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
8	C03B1.3	C03B1.3	n/a	chrX 6,366,380
9	R10F2.5	R10F2.5	n/a	chrIII 2,924,200	contains similarity to Interpro domain IPR000443 (Islet amyloid polypeptide)
10	B0554.7	B0554.7	n/a	chrV 439,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
11	srbc-65	Y32B12B.3	n/a	chrV 16,551,603	C. elegans SRBC-65 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
12	T23F4.1	T23F4.1	n/a	chrII 1,167,834	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
13	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
14	sri-25	C41G6.10	n/a	chrV 15,218,422	C. elegans SRI-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	ric-19	C32E8.7	n/a	chrI 3,779,897	The ric-19 gene encodes an evolutionarily conserved cytosolic protein involved in neuroendocrine secretion via association with secretory vesicles.
16	F56D5.9	F56D5.9	n/a	chrIV 9,420,446	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
17	C36C9.5	C36C9.5	n/a	chrX 1,701,859
18	sre-21	C47A10.4	n/a	chrV 17,771,397	C47A10.4 is orthologous to the human gene ALBINISM, OCULAR, TYPE I (OA1; OMIM:300500), which when mutated leads to Nettleship-Falls type ocular albinism.
19	W09D10.4	W09D10.4	n/a	chrIII 10,713,760	contains similarity to Pfam domain PF07228 Stage II sporulation protein E (SpoIIE) contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR010822 (Sporulation stage II, protein E C-terminal)
20	K07H8.5	K07H8.5	n/a	chrIV 8,272,091
21	R12C12.4	R12C12.4	n/a	chrII 6,039,457
22	F49D11.7	F49D11.7	n/a	chrI 10,923,733
23	M04D8.5	M04D8.5	n/a	chrIII 10,032,724	contains similarity to Periplaneta americana Large conductance calcium activated potassium channel pSlo spliceforms1-5A.; TR:Q8I9V1
24	T03E6.2	T03E6.2	n/a	chrV 16,582,078	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	C51E3.6	C51E3.6	n/a	chrV 10,165,329	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
26	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
27	Y66A7A.2	Y66A7A.2	n/a	chrIII 11,486,326	Y66A7A.2 encodes an ortholog of Pop5, a protein subunit shared by the endoribonucleases RNase MRP and RNAse P; RNAse MRP cleaves mitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA in ribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycle regulation; RNAse P cleaves tRNA precursors to produce their mature 5' end; Y66A7A.2 is evolutionarily ubiquitous among eukaryotes.
28	C54C8.3	C54C8.3	n/a	chrI 12,447,783	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
29	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
30	nhr-173	C56E10.1	n/a	chrX 6,657,606	C. elegans NHR-173 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	T26H2.5	T26H2.5	n/a	chrV 19,231,365	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
32	col-187	C30F2.1	n/a	chrX 16,073,795	C. elegans COL-187 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
33	T05B4.4	T05B4.4	n/a	chrV 4,128,560
34	srh-212	T22F3.6	n/a	chrV 3,596,155	C. elegans SRH-212 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
35	T20G5.4	T20G5.4	n/a	chrIII 10,213,504	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
36	str-211	C02E7.13	n/a	chrV 4,943,703	C. elegans STR-211 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	cyp-13A5	T10B9.2	n/a	chrII 9,799,242	C. elegans CYP-13A5 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
38	npr-1	C39E6.6	n/a	chrX 4,768,551	npr-1 encodes a predicted G protein-coupled neuropeptide receptor that is homologous to the mammalian neuropeptide Y (NPY) receptor (OMIM:162641) required for regulating anxiety, food consumption, and pain sensation; in C. elegans, NPR-1 is involved in ethological variations of social behavior such as social versus solitary feeding; NPR-1 also affects some aspect of UNC-6/netrin-mediated branching of motor neurons, as strong npr-1 mutations can suppress abnormal migration of ventral nerve cord neurons induced by overexpression of UNC-6 lacking domain C; NPR-1 is expressed predominantly in the nervous system, and particularly in the AQR, PQR, and URX neurons that are exposed to the body fluid.
39	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
40	gnrr-3	ZC374.1	n/a	chrX 10,050,904	C. elegans GNRR-3 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
41	F36F12.1	F36F12.1	n/a	chrV 2,101,648	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
42	C31H1.7	C31H1.7	n/a	chrIV 5,809,426
43	T08G3.7	T08G3.7	n/a	chrV 16,464,369	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
44	nhr-53	K06B4.11	n/a	chrV 15,701,459	C. elegans NHR-53 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	str-57	T06C12.2	n/a	chrV 15,871,734	C. elegans STR-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srx-104	F40H7.7	n/a	chrII 3,699,139	C. elegans SRX-104 protein ;
47	Y56A3A.16	Y56A3A.16	n/a	chrIII 11,912,267	contains similarity to Homo sapiens Isoform 1 of Pleckstrin homology domain-containing family M member 3; ENSEMBL:ENSP00000373899
48	gly-15	C54C8.11	n/a	chrI 12,463,985	gly-15 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-15 expressed only in cellular processes that are probably part of the secretory network of the G2 gland cells.
49	C31E10.4	C31E10.4	n/a	chrX 13,989,751
50	ikb-1	C04F12.3	n/a	chrI 9,687,053	ikb-1 encodes an ortholog of human BCL3 (OMIM:109560) that physically interacts with the checkpoint protein MRT-2; ikb-1(nr2019) and ikb-1(nr2027) mutants display no obvious phenotype other than shortened lifespan; mutation of BCL3 is frequently associated with recurring translocations found in the neoplastic cells of patients with chronic lymphocytic leukemia, and has been implicated in cell cycle control (perhaps via apoptosis).