UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	qui-1	Y45F10B.10	0	chrIV 13,568,114	The qui-1 gene encodes a protein of unknown function that contains several WD-40 domains.
2	K01A11.2	K01A11.2	n/a	chrIII 3,426,861	contains similarity to Xenopus laevis LOC495955 protein.; TR:Q5PQ79
3	T13C2.2	T13C2.2	n/a	chrII 6,795,686
4	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	F56C9.8	F56C9.8	n/a	chrIII 7,317,655
6	cof-2	C48E7.5	n/a	chrI 6,251,698	cof-2 encodes a homolog of human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750)
7	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
8	C34E11.2	C34E11.2	n/a	chrX 11,808,336	contains similarity to Pfam domain PF03166 MH2 domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000694 (Proline-rich region), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like)
9	W04G5.8	W04G5.8	n/a	chrI 11,650,893	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
10	srz-61	K03D3.4	n/a	chrIV 16,322,140	C. elegans SRZ-61 protein ;
11	C34E7.3	C34E7.3	n/a	chrX 12,931,101	contains similarity to Plasmodium falciparum Ribonuclease, putative.; TR:Q8ICL5
12	T13A10.1	T13A10.1	n/a	chrIV 6,276,666	contains similarity to Danio rerio Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).; SW:Q8JFV8
13	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
14	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
15	rps-8	F42C5.8	n/a	chrIV 7,313,435	rps-8 encodes a small ribosomal subunit S8 protein; by homology, RPS-8 is predicted to function in protein biosynthesis; in C. elegans, RPS-8 activity is required for germline development and the overall health of the animal.
16	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	Y6B3B.1	Y6B3B.1	n/a	chrI 13,699,504	contains similarity to Interpro domain IPR000533 (Tropomyosin)
18	nhr-70	Y51A2D.17	n/a	chrV 18,618,286	C. elegans NHR-70 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR002232 (5-Hydroxytryptamine 6 receptor)
19	clec-229	H02K04.1	n/a	chrV 15,340,763	C. elegans CLEC-229 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
20	T05C12.8	T05C12.8	n/a	chrII 8,189,001	contains similarity to Interpro domain IPR002110 (Ankyrin)
21	lgc-1	T05B4.1	n/a	chrV 4,136,911	C. elegans LGC-1 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
22	T07H6.4	T07H6.4	n/a	chrX 6,284,028	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR002396 (Selectin (CD62E/L/P antigen)), IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
23	C24A8.1	C24A8.1	n/a	chrX 4,323,582	C24A8.1 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3; C24A8.1 is expressed in the nervous system; because of its paralogy, C24A8.1 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants; but C24A8.1 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
24	F13A2.3	F13A2.3	n/a	chrV 4,394,967
25	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
26	F58F6.5	F58F6.5	n/a	chrIV 1,343,974	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domain IPR006874 (Protein of unknown function DUF621)
27	T27A8.5	T27A8.5	n/a	chrX 16,065,286	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
28	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
29	clec-192	Y116A8A.1	n/a	chrIV 16,803,039	C. elegans CLEC-192 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
30	src-2	F49B2.5	n/a	chrI 14,325,568	C. elegans SRC-2 protein; contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00018 (SH3 domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR000719 (Protein kinase, core), IPR013315 (Spectrin alpha chain), IPR011511 (Variant SH3), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
31	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	C38D9.5	C38D9.5	n/a	chrV 17,589,380	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
33	lact-3	M28.6	n/a	chrII 10,654,998	lact-3 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence; loss of lact-3 activity via RNAi has been reported to result in reduced fat content.
34	math-5	C16C4.10	n/a	chrII 1,882,210	C. elegans MATH-5 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
35	T14G11.1	T14G11.1	n/a	chrX 2,690,488
36	spe-38	Y52B11A.1	n/a	chrI 10,965,401	C. elegans SPE-38 protein ;
37	srj-5	F31F4.16	n/a	chrV 652,439	C. elegans SRJ-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	snt-6	C08G5.4	n/a	chrII 747,906	C. elegans SNT-6 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
39	F25H2.2	F25H2.2	n/a	chrI 10,544,713	contains similarity to Pfam domains PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00787 (PX domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR001683 (Phox-like), IPR001478 (PDZ/DHR/GLGF)
40	shw-3	R186.5	n/a	chrV 12,974,845	C. elegans SHW-3 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003973 (Potassium channel, voltage dependent, Kv2), IPR003970 (Potassium channel, voltage dependent, Kv8), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003969 (Potassium channel, voltage dependent, Kv6), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
41	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
42	bbs-9	C48B6.8	n/a	chrI 6,920,270	C. elegans BBS-9 protein ; contains similarity to Homo sapiens 95 kDa protein; ENSEMBL:ENSP00000346214
43	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
44	tag-117	C01B7.4	n/a	chrV 8,794,107	C. elegans TAG-117 protein; contains similarity to Pfam domains PF00018 (SH3 domain) , PF00625 (Guanylate kinase) , PF07653 (Variant SH3 domain) , PF00595 (PDZ domain (Also known as DHR or GLGF)) contains similarity to Interpro domains IPR011511 (Variant SH3), IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001478 (PDZ/DHR/GLGF), IPR001452 (Src homology-3)
45	srd-5	T19E7.5	n/a	chrIV 5,673,565	C. elegans SRD-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR004268 (Virulence factor MVIN-like)
46	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
47	str-149	Y32B12B.5	n/a	chrV 16,574,182	C. elegans STR-149 protein ;
48	nhr-280	C29F9.13	n/a	chrIII 130,464	C. elegans NHR-280 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	col-162	Y2H9A.3	n/a	chrV 13,442,665	C. elegans COL-162 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
50	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)