UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ttr-24	Y51A2D.9	2e-78	chrV 18,555,981	C. elegans TTR-24 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	nhr-19	E02H1.7	n/a	chrII 9,601,747	C. elegans NHR-19 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	spp-8	C28C12.5	n/a	chrIV 8,482,669	C. elegans SPP-8 protein; contains similarity to Pfam domain PF03489 Saposin-like type B, region 2 contains similarity to Interpro domains IPR008138 (Saposin-like type B, 2), IPR011001 (Saposin-like), IPR008139 (Saposin B)
5	Y51B9A.9	Y51B9A.9	n/a	chrII 9,396,480	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	pqn-92	Y75B8A.27	n/a	chrIII 12,309,726	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
7	snb-2	F23H12.1	n/a	chrV 12,345,050	C. elegans SNB-2 protein; contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR016444 (Synaptobrevin, metazoa/fungi), IPR001388 (Synaptobrevin)
8	pph-1	C05A2.1	n/a	chrV 10,703,698	C. elegans PPH-1 protein; contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
9	T10G3.2	T10G3.2	n/a	chrV 13,478,579	contains similarity to Mus musculus Transmembrane protein TIARP.; TR:Q91W31
10	cal-1	C13C12.1	n/a	chrV 12,515,481	cal-1 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-2, CAL-3, CAL-4, and CMD-1); as loss of cal-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-1 in C. elegans development and/or behavior is not yet known.
11	B0207.10	B0207.10	n/a	chrI 5,959,278
12	F15B9.6	F15B9.6	n/a	chrV 13,015,372	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
13	glc-1	F11A5.10	n/a	chrV 16,220,736	glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin.
14	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
15	K02F3.9	K02F3.9	n/a	chrIII 840,905
16	T23F4.3	T23F4.3	n/a	chrII 1,170,980	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
17	str-199	Y68A4A.3	n/a	chrV 17,189,811	C. elegans STR-199 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	fbxa-195	R09B5.1	n/a	chrV 1,435,696	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
19	C49D10.8	C49D10.8	n/a	chrII 3,859,527	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
20	srsx-2	F20E11.2	n/a	chrV 17,437,669	C. elegans SRSX-2 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
21	srj-16	T06A1.2	n/a	chrV 1,955,236	C. elegans SRJ-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	clec-2	B0454.7	n/a	chrII 3,021,991	C. elegans CLEC-2 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	F13C5.1	F13C5.1	n/a	chrX 603,249
24	srbc-24	C45H4.10	n/a	chrV 2,152,386	C. elegans SRBC-24 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
25	B0507.2	B0507.2	n/a	chrV 8,775,382	contains similarity to Interpro domain IPR004328 (BRO1)
26	F25E5.5	F25E5.5	n/a	chrV 7,448,059	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
27	ZC196.1	ZC196.1	n/a	chrV 8,744,495
28	ZC239.13	ZC239.13	n/a	chrII 3,222,611	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
29	fbxb-6	F07E5.1	n/a	chrII 2,066,717	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	C32B5.3	C32B5.3	n/a	chrII 981,863
31	tag-244	C34H4.3	n/a	chrIV 1,551,970	C. elegans TAG-244 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
32	C04E6.7	C04E6.7	n/a	chrV 5,894,251	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR016059 (ATP-dependent DNA ligase, conserved site), IPR005834 (Haloacid dehalogenase-like hydrolase)
33	rlbp-1	T23G11.5	n/a	chrI 7,688,763	C. elegans RLBP-1 protein; contains similarity to Pfam domain PF00620 RhoGAP domain contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR000198 (RhoGAP)
34	F16G10.15	F16G10.15	n/a	chrII 2,406,470	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
35	T23B3.1	T23B3.1	n/a	chrI 6,718,630
36	hex-1	T14F9.3	n/a	chrX 2,225,047	hex-1 encodes a beta-N-acetylhexosaminidase that is orthologous to the human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB; OMIM:606873), which when mutated leads to disease.
37	srj-29	F22B8.1	n/a	chrV 16,076,456	C. elegans SRJ-29 protein; contains similarity to Pfam domains PF00060 (Ligand-gated ion channel) , PF01094 (Receptor family ligand binding region) contains similarity to Interpro domains IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR015683 (Glutamate receptor-related), IPR001320 (Ionotropic glutamate receptor), IPR001828 (Extracellular ligand-binding receptor), IPR001508 (NMDA receptor)
38	B0462.1	B0462.1	n/a	chrV 18,326,871	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
39	F58G4.3	F58G4.3	n/a	chrV 8,105,172	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
40	ZK1073.1	ZK1073.1	n/a	chrX 16,126,525	contains similarity to Pfam domain PF03096 Ndr family contains similarity to Interpro domain IPR004142 (Ndr)
41	C17B7.12	C17B7.12	n/a	chrV 3,353,590
42	srx-128	F55B12.7	n/a	chrV 13,838,056	C. elegans SRX-128 protein ;
43	srz-31	H12I19.2	n/a	chrIV 14,138,796	C. elegans SRZ-31 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	B0496.5	B0496.5	n/a	chrIV 7,421,847	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
45	ceh-28	K03A11.3	n/a	chrX 13,075,231	A homeobox protein of the NK-2 family; it is expressed in a single pharyngeal neuron, M4.
46	Y76A2B.5	Y76A2B.5	n/a	chrIII 13,547,827	contains similarity to Danio rerio Zgc:91819 protein.; TR:Q6GMH4
47	K09C4.9	K09C4.9	n/a	chrX 3,271,553
48	srp-6	C03G6.19	n/a	chrV 7,385,156	srp-6 encodes a functional serpin (serine protease inhibitor)
49	K04F10.2	K04F10.2	n/a	chrI 6,362,454	contains similarity to Interpro domain IPR008979 (Galactose-binding like)
50	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.