UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC190.5	ZC190.5	5e-179	chrV 8,672,433
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	F42G9.4	F42G9.4	n/a	chrIII 761,894
4	E03A3.5	E03A3.5	n/a	chrIII 4,061,679	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold)
5	lin-33	H32C10.2	n/a	chrIV 5,931,939	C. elegans LIN-33 protein; contains similarity to Interpro domain IPR002873 (Non-structural protein NSP3, Rotavirus)
6	nhr-207	R07B7.14	n/a	chrV 12,097,016	C. elegans NHR-207 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR001728 (Thyroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	trpa-1	C29E6.2	n/a	chrIV 11,870,347	trpa-1 encodes a transient receptor potential (TRP) ion channel orthologous to the vertebrate and Drosophila TRPA1 channels; in C. elegans, trpa-1 activity is required for specific mechanosensory behaviors such as nose-touch avoidance and touch-mediated foraging; when expressed in mammalian cells, TRPA-1 exhibits channel activity in response to mechanical stimulation; TRPA-1::GFP reporters are expressed in a number of different cell types including sensory neurons, muscle, and epithelial cells.
8	C52E4.5	C52E4.5	n/a	chrV 11,984,169	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
9	F49E10.1	F49E10.1	n/a	chrX 5,899,725	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
10	ZC416.1	ZC416.1	n/a	chrIV 3,637,332	n/a
11	F55A4.2	F55A4.2	n/a	chrX 1,015,147
12	M01G4.1	M01G4.1	n/a	chrIII 6,665,107
13	T07D3.4	T07D3.4	n/a	chrII 889,513	T07D3.4 is orthologous to the human gene FUKUTIN (FCMD; OMIM:253800), which when mutated leads to disease.
14	T23G5.6	T23G5.6	n/a	chrIII 9,241,340	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
15	lgc-34	T27A1.4	n/a	chrII 528,462	C. elegans LGC-34 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
16	R08C7.4	R08C7.4	n/a	chrIV 4,436,206	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
17	F09G8.3	F09G8.3	n/a	chrIII 8,266,869	contains similarity to Pfam domain PF00380 Ribosomal protein S9/S16 contains similarity to Interpro domains IPR000754 (Ribosomal protein S9), IPR014721 (Ribosomal protein S5 domain 2-type fold)
18	gur-4	K09E4.5	n/a	chrII 14,106,298	C. elegans GUR-4 protein ;
19	sgn-1	F07H5.2	n/a	chrII 8,782,783	C. elegans SGN-1 protein; contains similarity to Pfam domain PF04790 Sarcoglycan complex subunit protein contains similarity to Interpro domain IPR006875 (Sarcoglycan complex subunit protein)
20	rgs-6	C41G11.3	n/a	chrX 5,724,513	rgs-6 encodes a regulator of G protein signaling; by homology, RGS-6 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-6 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-6 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the rgs-6 expression pattern has not yet been reported.
21	K08B12.3	K08B12.3	n/a	chrV 6,236,378	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006355 (HAD-superfamily hydrolase, subfamily IIA, hypothetical 2), IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
22	C45G7.4	C45G7.4	n/a	chrIV 2,434,709	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
23	daf-14	F01G10.8	n/a	chrIV 10,254,701	daf-14 encodes a Smad-related protein that is unusual in that while its C-terminus is well-conserved with Smad proteins, it lacks the N-terminal DNA binding domain found in all other known Smads; DAF-14 is predicted to function as a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and negatively regulates dauer formation; as reduction of daf-14 function enhances the dauer constitutive phenotype of daf-8 mutants, and overexpression of daf-14 can rescue daf-8 mutant animals, it is likely that the DAF-14 and DAF-8 Smad proteins function in parallel to control dauer formation; further genetic analyses suggest that DAF-14 and DAF-8 function to antagonize the activities of the DAF-3 Smad and DAF-5 Sno/Ski oncoprotein, which are required for dauer formation; a DAF-14::GFP reporter is expressed in a dynamic pattern in tissues, such as the hypodermis, intestine, and pharynx, that are remodeled during dauer development.
24	M176.4	M176.4	n/a	chrII 9,421,150	contains similarity to Pfam domain PF07947 YhhN-like protein contains similarity to Interpro domains IPR012506 (YhhN-like), IPR003492 (Batten's disease protein Cln3)
25	F38B6.1	F38B6.1	n/a	chrX 6,700,523
26	H19J13.1	H19J13.1	n/a	chrX 12,268,942	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
27	cst-2	C24A8.4	n/a	chrX 4,334,568	C. elegans CST-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
28	E04F6.4	E04F6.4	n/a	chrII 7,190,903	contains similarity to Pfam domains PF08371 (Phospholipase D/viral envelope) , PF00614 (Phospholipase D Active site motif) (2)contains similarity to Interpro domains IPR013582 (Phospholipase D/viral envelope), IPR001736 (Phospholipase D/Transphosphatidylase)
29	K08E7.6	K08E7.6	n/a	chrIV 12,580,060	contains similarity to Aquifex aeolicus Probable DNA double-strand break repair rad50 ATPase.; SW:RA50_AQUAE
30	F43G6.7	F43G6.7	n/a	chrII 11,811,141	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003980 (Histamine H3 receptor)
31	lev-1	F09E8.7	n/a	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
32	R05D7.4	R05D7.4	n/a	chrI 12,182,156	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like), IPR000639 (Epoxide hydrolase-like), IPR008262 (Lipase, active site), IPR003089 (Alpha/beta hydrolase)
33	srx-36	T01C4.6	n/a	chrV 7,130,371	C. elegans SRX-36 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
34	srh-174	F40D4.1	n/a	chrV 17,179,348	C. elegans SRH-174 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	F53B1.8	F53B1.8	n/a	chrX 2,126,824	contains similarity to Interpro domain IPR001441 (Di-trans-poly-cis-decaprenylcistransferase)
36	elt-3	K02B9.4	n/a	chrX 13,939,895	The elt-3 gene encodes a GATA transcription factor expressed in the embryonic hypodermis; specifically, it is expressed in expressed in all of the major hypodermal cells except the lateral seam cells.
37	F59B10.3	F59B10.3	n/a	chrII 10,511,687	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
38	rpy-1	C18H9.7	n/a	chrII 6,703,848	rpy-1 is orthologous to the human gene 43KDA ACETYLCHOLINE RECEPTOR-ASSOCIATED PROTEIN (RAPSN; OMIM:601592), which when mutated leads to congenital myasthenic syndrome.
39	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	W04G5.8	W04G5.8	n/a	chrI 11,650,893	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
41	pac-1	C04D8.1	n/a	chrIII 8,508,167	C. elegans PAC-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR001849 (Pleckstrin-like), IPR000104 (Antifreeze protein, type I), IPR011993 (Pleckstrin homology-type), IPR000198 (RhoGAP)
42	F31F7.2	F31F7.2	n/a	chrV 6,272,906	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
43	F47G4.5	F47G4.5	n/a	chrI 14,061,493	F47G4.5 encodes a paralog of MEI-2 that, like MEI-2, binds MEI-1 in vitro; F47G4.5 might thus be an alternative ligand of MEI-1 in vivo.
44	F21F8.6	F21F8.6	n/a	chrV 8,266,564
45	C50F2.8	C50F2.8	n/a	chrI 3,903,318	contains similarity to Pfam domains PF00018 (SH3 domain) , PF00625 (Guanylate kinase) contains similarity to Interpro domains IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001452 (Src homology-3), IPR001478 (PDZ/DHR/GLGF)
46	C17E4.11	C17E4.11	n/a	chrI 9,420,385	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
47	C09F12.2	C09F12.2	n/a	chrX 11,055,383	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23C46
48	fozi-1	K01B6.1	n/a	chrIII 9,291,244	fozi-1 encodes an unusual zinc-finger protein that has two C2H2 zinc-finger motifs that probably mediate transcriptional regulation along with a glutamine-rich region and a vestigial formin homology 2 (FH2) domain that has lost its ability to polymerize actin but retained its ability to dimerize; during postembryonic development, FOZI-1 acts with MAB-5 and redundantly with HLH-1/CeMyoD to autonomously specify coelomocyte and striated body wall muscle fates; in addition, fozi-1 is required for the fully asymmetrical phenotypic distinction of ASER cells from ASEL cells; fozi-1 mutant animals variably express flp-4, gcy-6, gcy-7 and lim-6, genes normally restricted to ASEL, in ASER as well, while maintaining expression of ASER-specific genes; ectopic FOZI-1 expression in ASEL can suppress lim-6 expression; fozi-1 genetically interacts with several regulatory proteins and miRNAs; FOZI-1 is a nuclear protein that is expressed in neuronal lineages beginning at the 2-fold stage of embryogenesis, and then in neurons and cells derived from the M mesoblast during larval development; expression in the M lineage corresponds to cells that will generate coelomocytes and body wall muscles and is not seen in the sex myoblasts (SMs); FOZI-1 expression in the M lineage requires the Hox co-factor CEH-20.
49	tag-278	C02F12.7	n/a	chrX 3,686,384	C. elegans TAG-278 protein; contains similarity to Interpro domain IPR000533 (Tropomyosin)
50	M03F8.4	M03F8.4	n/a	chrV 5,932,159	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)