Gene interactions and pathways from curated databases and text-mining
IL6: top 25 interacting genes (chr7:22766818-22771617)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-IL6 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with IL6, not among the Top 25
Other genes interacting with IL6. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M ▸ ABCA4 ▸ ABCB1 ▸ ABCC1 ▸ ABCG2 ▸ ABL1 ▸ ACAN ▸
ACD ▸ ACE ▸ ACE2 ▸ ACHE ▸ ACP2 ▸ ACR ▸ ACSM3 ▸
AD5 ▸ ADAM17 ▸ ADCY1 ▸ ADCY10 ▸ ADCY2 ▸ ADCY3 ▸ ADCY4 ▸
ADCY5 ▸ ADCY6 ▸ ADCY7 ▸ ADCY8 ▸ ADCY9 ▸ ADCYAP1 ▸ ADH4 ▸
ADH5 ▸ ADH6 ▸ ADH7 ▸ ADIPOQ ▸ ADIPOR1 ▸ ADM ▸ ADORA1 ▸
ADORA3 ▸ AGT ▸ AGTR1 ▸ AGTR2 ▸ AHR ▸ AHSA1 ▸ AHSG ▸
AIF1 ▸ AKT1 ▸ AKT2 ▸ AKT3 ▸ ALB ▸ ALG1 ▸ AMELX ▸
ANG ▸ ANGPT1 ▸ ANGPT2 ▸ ANGPT4 ▸ ANPEP ▸ ANXA1 ▸ ANXA6 ▸
APC ▸ APCS ▸ APOA4 ▸ APOB ▸ APOE ▸ APP ▸ AR ▸
AREG ▸ ARG1 ▸ ARG2 ▸ ARID4B ▸ ARSA ▸ ASIP ▸ ATF1 ▸
ATF3 ▸ ATF4 ▸ ATP5O ▸ ATP7A ▸ ATP8A2 ▸ AVP ▸ AZU1 ▸
BAI1 ▸ BAI2 ▸ BAI3 ▸ BAX ▸ BCL10 ▸ BCL2 ▸ BCL3 ▸
BCL5 ▸ BCL6 ▸ BCL9 ▸ BCR ▸ BDNF ▸ BGLAP ▸ BLVRB ▸
BMP1 ▸ BMP10 ▸ BMP15 ▸ BMP2 ▸ BMP3 ▸ BMP4 ▸ BMP5 ▸
BMP6 ▸ BMP7 ▸ BPI ▸ BSG ▸ BTK ▸ BTRC ▸ C1QA ▸
C1QB ▸ C1orf228 ▸ C3AR1 ▸ C4BPA ▸ C5 ▸ C5AR1 ▸ CA1 ▸
CA2 ▸ CALCA ▸ CALM1 ▸ CALM2 ▸ CALM3 ▸ CALML3 ▸ CASP1 ▸
CASP10 ▸ CASP12 ▸ CASP14 ▸ CASP16 ▸ CASP2 ▸ CASP3 ▸ CASP4 ▸
CASP5 ▸ CASP6 ▸ CASP7 ▸ CASP8 ▸ CASP9 ▸ CAT ▸ CAV1 ▸
CAV2 ▸ CAV3 ▸ CBL ▸ CCK ▸ CCL1 ▸ CCL2 ▸ CCL20 ▸
CCL3 ▸ CCL4 ▸ CCL5 ▸ CCND1 ▸ CCR1 ▸ CCR2 ▸ CCR5 ▸
CCR6 ▸ CD14 ▸ CD163 ▸ CD19 ▸ CD1C ▸ CD1D ▸ CD2 ▸
CD274 ▸ CD28 ▸ CD33 ▸ CD34 ▸ CD38 ▸ CD4 ▸ CD40 ▸
CD40LG ▸ CD44 ▸ CD46 ▸ CD5 ▸ CD59 ▸ CD69 ▸ CD79A ▸
CD80 ▸ CD86 ▸ CD8A ▸ CD8B ▸ CDC73 ▸ CDH1 ▸ CDK4 ▸
CDK9 ▸ CDKN1A ▸ CDKN1B ▸ CDKN2A ▸ CEACAM1 ▸ CEACAM5 ▸ CEBPA ▸
CEBPB ▸ CEBPD ▸ CEBPZ ▸ CHAT ▸ CHGA ▸ CHP1 ▸ CHP2 ▸
CHUK ▸ CIB1 ▸ CISH ▸ CLEC7A ▸ CLU ▸ CNR2 ▸ CNTF ▸
CNTN2 ▸ COL1A1 ▸ COQ2 ▸ COQ3 ▸ COQ4 ▸ COQ5 ▸ COQ6 ▸
COQ7 ▸ COQ9 ▸ CORT ▸ CP ▸ CPA1 ▸ CPB1 ▸ CPB2 ▸
CPOX ▸ CR2 ▸ CRAT ▸ CREB1 ▸ CREB3 ▸ CREB5 ▸ CREBBP ▸
CRH ▸ CRK ▸ CRP ▸ CRYGEP ▸ CSE ▸ CSF1 ▸ CSF2 ▸
CSF3 ▸ CSH2 ▸ CSK ▸ CSRP1 ▸ CTF1 ▸ CTGF ▸ CTR9 ▸
CTSB ▸ CTSL ▸ CTSS ▸ CUL1 ▸ CX3CL1 ▸ CX3CR1 ▸ CXCL1 ▸
CXCL10 ▸ CXCL11 ▸ CXCL12 ▸ CXCL13 ▸ CXCL14 ▸ CXCL16 ▸ CXCL17 ▸
CXCL2 ▸ CXCL3 ▸ CXCL5 ▸ CXCL6 ▸ CXCL9 ▸ CXCR3 ▸ CXCR4 ▸
CYP19A1 ▸ CYP1A1 ▸ CYP1A2 ▸ CYP3A ▸ CYP3A4 ▸ DDIT3 ▸ DEFB114 ▸
DEFB4B ▸ DERL1 ▸ DNMT1 ▸ DUSP1 ▸ DYNLRB1 ▸ E2F1 ▸ EBP ▸
ECM1 ▸ ECM2 ▸ EDN1 ▸ EDN2 ▸ EDN3 ▸ EDNRA ▸ EEF1A2 ▸
EGF ▸ EGFR ▸ EGR1 ▸ EIF2AK2 ▸ EPHB2 ▸ EPO ▸ EPS15 ▸
EPS8 ▸ EPX ▸ ERBB3 ▸ EREG ▸ ERVK-6 ▸ ESR1 ▸ ESR2 ▸
ETS1 ▸ ETS2 ▸ F12 ▸ F2R ▸ F2RL1 ▸ FAS ▸ FASLG ▸
FCER2 ▸ FCGR1A ▸ FGB ▸ FGF1 ▸ FGF10 ▸ FGF11 ▸ FGF12 ▸
FGF13 ▸ FGF14 ▸ FGF16 ▸ FGF17 ▸ FGF18 ▸ FGF19 ▸ FGF2 ▸
FGF20 ▸ FGF21 ▸ FGF22 ▸ FGF23 ▸ FGF3 ▸ FGF4 ▸ FGF5 ▸
FGF6 ▸ FGF7 ▸ FGF8 ▸ FGF9 ▸ FGFR2 ▸ FGFR3 ▸ FGL1 ▸
FLOT2 ▸ FLT3LG ▸ FMR1 ▸ FOS ▸ FOXO1 ▸ FOXO3 ▸ FOXP3 ▸
FUT4 ▸ FXR1 ▸ FXR2 ▸ FXYD1 ▸ FYN ▸ GAL ▸ GAS6 ▸
GAST ▸ GCG ▸ GCLC ▸ GCSAM ▸ GFAP ▸ GH1 ▸ GHRH ▸
GIF ▸ GIP ▸ GNA13 ▸ GNRH1 ▸ GP2 ▸ GP5 ▸ GP6 ▸
GP9 ▸ GPI ▸ GPX1 ▸ GPX2 ▸ GPX3 ▸ GPX4 ▸ GPX5 ▸
GPX6 ▸ GPX7 ▸ GPX8 ▸ GRAP2 ▸ GRB2 ▸ GSTM1 ▸ GSTM2 ▸
GSTM3 ▸ GSTM4 ▸ GSTM5 ▸ GTF2B ▸ GYS1 ▸ GYS2 ▸ GZMB ▸
HAMP ▸ HBD ▸ HCFC1 ▸ HCK ▸ HCL1 ▸ HCL2 ▸ HCL3 ▸
HDAC1 ▸ HDAC10 ▸ HDAC11 ▸ HDAC2 ▸ HDAC3 ▸ HDAC4 ▸ HDAC5 ▸
HDAC6 ▸ HDAC7 ▸ HDAC8 ▸ HDAC9 ▸ HDC ▸ HES1 ▸ HES2 ▸
HES3 ▸ HES4 ▸ HES5 ▸ HES6 ▸ HES7 ▸ HGF ▸ HIF1A ▸
HLA-DRA ▸ HLA-DRB1 ▸ HMGB1 ▸ HMGCR ▸ HMOX1 ▸ HNRNPA1 ▸ HNRNPF ▸
HNRNPH1 ▸ HP ▸ HPD ▸ HPX ▸ HRAS ▸ HSF1 ▸ HSP90AA1 ▸
HSP90AB1 ▸ HSPA5 ▸ HSPB1 ▸ HSPB3 ▸ HSPB8 ▸ HSPD1 ▸ HSPG2 ▸
IBD2 ▸ IBD3 ▸ IBD4 ▸ IBD5 ▸ IBD6 ▸ IBD7 ▸ IBD8 ▸
IBD9 ▸ ICAM1 ▸ ICAM2 ▸ ICAM3 ▸ ICAM4 ▸ ICAM5 ▸ ICOS ▸
ICOSLG ▸ IDO1 ▸ IDS ▸ IFI27 ▸ IFI44 ▸ IFIT1 ▸ IFNA1 ▸
IFNA10 ▸ IFNA13 ▸ IFNA14 ▸ IFNA16 ▸ IFNA17 ▸ IFNA2 ▸ IFNA21 ▸
IFNA4 ▸ IFNA5 ▸ IFNA6 ▸ IFNA7 ▸ IFNA8 ▸ IFNB1 ▸ IGF1 ▸
IGF1R ▸ IGF2 ▸ IGFBP1 ▸ IGFBP2 ▸ IGFBP3 ▸ IGFBP4 ▸ IGFBP5 ▸
IGFBP7 ▸ IKBKB ▸ IKBKG ▸ IL11 ▸ IL12A ▸ IL12B ▸ IL13 ▸
IL15 ▸ IL16 ▸ IL17A ▸ IL17D ▸ IL17F ▸ IL17RA ▸ IL18 ▸
IL19 ▸ IL1R1 ▸ IL1R2 ▸ IL1RAP ▸ IL1RN ▸ IL20 ▸ IL21 ▸
IL22 ▸ IL23A ▸ IL24 ▸ IL25 ▸ IL26 ▸ IL27 ▸ IL2RA ▸
IL2RB ▸ IL2RG ▸ IL3 ▸ IL31 ▸ IL32 ▸ IL33 ▸ IL34 ▸
IL37 ▸ IL5 ▸ IL6R ▸ IL6ST ▸ IL7 ▸ IL9 ▸ INA ▸
INS ▸ IRAK1 ▸ IRAK2 ▸ IRAK3 ▸ IRAK4 ▸ IRF1 ▸ IRF2 ▸
IRF3 ▸ IRF4 ▸ IRF5 ▸ IRF7 ▸ IRF8 ▸ IRF9 ▸ IRG1 ▸
IRS1 ▸ ITGA2B ▸ ITGA4 ▸ ITGA5 ▸ ITGAM ▸ ITGB1 ▸ ITIH4 ▸
JAK1 ▸ JAK2 ▸ JAK3 ▸ JUN ▸ JUNB ▸ JUND ▸ KAT2B ▸
KDR ▸ KITLG ▸ KLK3 ▸ KLRB1 ▸ KNG1 ▸ KRT10 ▸ KRT13 ▸
KRT37 ▸ KRT38 ▸ LBP ▸ LCAT ▸ LCN2 ▸ LDLR ▸ LEO1 ▸
LEP ▸ LGALS1 ▸ LGALS3 ▸ LIF ▸ LPA ▸ LPL ▸ LRG1 ▸
LRPPRC ▸ LTA ▸ LTB ▸ LTF ▸ LYN ▸ LYZ ▸ MAF ▸
MAL ▸ MAP2K1 ▸ MAP2K2 ▸ MAP2K3 ▸ MAP2K4 ▸ MAP2K5 ▸ MAP2K6 ▸
MAP2K7 ▸ MAP3K3 ▸ MAP3K7 ▸ MAPK9 ▸ MAPKAPK2 ▸ MBP ▸ MCC ▸
MCL1 ▸ MCS ▸ MEOX2 ▸ MEPE ▸ MET ▸ MIA ▸ MICE ▸
MIF ▸ MIP ▸ MKL1 ▸ MMP1 ▸ MMP10 ▸ MMP11 ▸ MMP12 ▸
MMP13 ▸ MMP14 ▸ MMP15 ▸ MMP16 ▸ MMP17 ▸ MMP19 ▸ MMP2 ▸
MMP20 ▸ MMP21 ▸ MMP24 ▸ MMP25 ▸ MMP26 ▸ MMP27 ▸ MMP28 ▸
MMP3 ▸ MMP7 ▸ MMP8 ▸ MMP9 ▸ MOG ▸ MPG ▸ MPL ▸
MPO ▸ MRXS5 ▸ MS4A1 ▸ MSC ▸ MSH2 ▸ MSH3 ▸ MSH4 ▸
MSH5 ▸ MSH6 ▸ MT3 ▸ MT4 ▸ MTA1 ▸ MTA2 ▸ MTA3 ▸
MTOR ▸ MTX1 ▸ MUC1 ▸ MUC12 ▸ MUC13 ▸ MUC15 ▸ MUC16 ▸
MUC17 ▸ MUC19 ▸ MUC2 ▸ MUC20 ▸ MUC21 ▸ MUC22 ▸ MUC4 ▸
MUC5AC ▸ MUC6 ▸ MUC7 ▸ MUC8 ▸ MYC ▸ MYD88 ▸ MYLIP ▸
MYO10 ▸ MYO16 ▸ MYO19 ▸ MYO6 ▸ NA ▸ NAALADL1 ▸ NAMPT ▸
NANOG ▸ NCAM1 ▸ NDP ▸ NEUROD1 ▸ NEUROD2 ▸ NEUROD4 ▸ NEUROD6 ▸
NFATC2 ▸ NFKB2 ▸ NFKBIA ▸ NGF ▸ NLRC5 ▸ NLRP3 ▸ NM ▸
NMU ▸ NNMT ▸ NOD1 ▸ NOD2 ▸ NOS1 ▸ NOS2 ▸ NOS3 ▸
NOTCH1 ▸ NOTCH2 ▸ NOX1 ▸ NOX3 ▸ NOX4 ▸ NOX5 ▸ NPEPPS ▸
NPPA ▸ NPS ▸ NPY ▸ NPY4R ▸ NR0B1 ▸ NR4A1 ▸ NT5E ▸
NTF3 ▸ NTF4 ▸ NTN1 ▸ NTS ▸ NUP43 ▸ OAS1 ▸ OAS2 ▸
OAS3 ▸ OPN1LW ▸ OPRM1 ▸ OSM ▸ OXA1L ▸ OXTR ▸ P2RX1 ▸
P2RX7 ▸ P2RY6 ▸ PAEP ▸ PAF1 ▸ PAM ▸ PARK2 ▸ PARK7 ▸
PARP1 ▸ PARP10 ▸ PARP11 ▸ PARP12 ▸ PARP14 ▸ PARP15 ▸ PARP16 ▸
PARP2 ▸ PARP3 ▸ PARP4 ▸ PARP6 ▸ PARP8 ▸ PARP9 ▸ PC ▸
PCK1 ▸ PCK2 ▸ PDAP1 ▸ PDCD1 ▸ PDCD10 ▸ PDCD11 ▸ PDCD2 ▸
PDCD4 ▸ PDCD5 ▸ PDCD6 ▸ PDCD7 ▸ PDGFA ▸ PDGFB ▸ PDLIM7 ▸
PGD ▸ PGF ▸ PGP ▸ PHB ▸ PI3 ▸ PIAS1 ▸ PIAS3 ▸
PIGA ▸ PIK3C3 ▸ PIK3CA ▸ PIK3R1 ▸ PIM1 ▸ PINK1 ▸ PITX2 ▸
PLA2G1B ▸ PLA2G2D ▸ PLA2G4A ▸ PLAT ▸ PLD1 ▸ PLD2 ▸ PLD3 ▸
PLD4 ▸ PLD5 ▸ PLD6 ▸ PLG ▸ POLDIP2 ▸ POMC ▸ PON1 ▸
POU5F1 ▸ PPARA ▸ PPARG ▸ PPP2CA ▸ PPP2R1A ▸ PPP2R2B ▸ PPP5C ▸
PRDX2 ▸ PRG2 ▸ PRG3 ▸ PRG4 ▸ PRKAA1 ▸ PRKAA2 ▸ PRKAB1 ▸
PRKAB2 ▸ PRKACB ▸ PRKACG ▸ PRKAG1 ▸ PRKAG2 ▸ PRKAR1A ▸ PRKAR1B ▸
PRKAR2A ▸ PRKAR2B ▸ PRKCA ▸ PRKD1 ▸ PRL ▸ PRNP ▸ PSMB9 ▸
PTBP1 ▸ PTBP2 ▸ PTGER4 ▸ PTGS1 ▸ PTGS2 ▸ PTH ▸ PTHLH ▸
PTK2 ▸ PTK2B ▸ PTK6 ▸ PTK7 ▸ PTPN11 ▸ PTPN22 ▸ PTPN4 ▸
PTPRC ▸ PTPRE ▸ PTS ▸ PTX3 ▸ PTX4 ▸ QRICH1 ▸ QRICH2 ▸
RAB7A ▸ RAB7B ▸ RABEPK ▸ RAC1 ▸ RAF1 ▸ RAG1 ▸ RAG2 ▸
RASIP1 ▸ RB1 ▸ RBBP4 ▸ RBBP7 ▸ RBP4 ▸ REG1A ▸ REL ▸
REN ▸ RENBP ▸ RETN ▸ RHO ▸ RLN1 ▸ RLN2 ▸ RLN3 ▸
RNASE3 ▸ RNF19A ▸ ROR1 ▸ ROR2 ▸ RORC ▸ RPL17 ▸ RPS6KA3 ▸
RUNX2 ▸ S100A12 ▸ S100A8 ▸ S100A9 ▸ S100B ▸ SAA1 ▸ SAA2 ▸
SAA3P ▸ SAA4 ▸ SAP130 ▸ SAP30 ▸ SARS ▸ SCARB1 ▸ SCG2 ▸
SCG3 ▸ SCG5 ▸ SDC1 ▸ SEA ▸ SELE ▸ SELL ▸ SELP ▸
SERPINA1 ▸ SERPINA3 ▸ SERPINA6 ▸ SERPINB5 ▸ SERPINE1 ▸ SERPINE2 ▸ SERPINF1 ▸
SERPING1 ▸ SETBP1 ▸ SETD2 ▸ SFTPA1 ▸ SFTPC ▸ SH3GL2 ▸ SHC1 ▸
SIN3A ▸ SKP1 ▸ SLC25A3 ▸ SLC33A1 ▸ SLC39A14 ▸ SLPI ▸ SMAD1 ▸
SMAD2 ▸ SMAD3 ▸ SMAD4 ▸ SMAD5 ▸ SMAD6 ▸ SMAD7 ▸ SMAD9 ▸
SMC2 ▸ SMC3 ▸ SMC4 ▸ SMC5 ▸ SMC6 ▸ SMN1 ▸ SOAT1 ▸
SOCS1 ▸ SOCS3 ▸ SOD1 ▸ SOD2 ▸ SOD3 ▸ SOS1 ▸ SP1 ▸
SP3 ▸ SPN ▸ SPP1 ▸ SRC ▸ SST ▸ ST2 ▸ STAT1 ▸
STAT4 ▸ STAT5A ▸ STEAP4 ▸ STK10 ▸ STK11 ▸ STK16 ▸ STK19 ▸
STK24 ▸ STK25 ▸ STK3 ▸ STK31 ▸ STK33 ▸ STK35 ▸ STK36 ▸
STK38 ▸ STK39 ▸ STK4 ▸ STK40 ▸ STS ▸ SUDS3 ▸ SYK ▸
SYT1 ▸ TAB1 ▸ TAC1 ▸ TAC3 ▸ TAC4 ▸ TAT ▸ TBCC ▸
TBP ▸ TCF12 ▸ TCF15 ▸ TCF19 ▸ TCF20 ▸ TCF21 ▸ TCF23 ▸
TCF24 ▸ TCF25 ▸ TCF3 ▸ TCF4 ▸ TCF7 ▸ TEC ▸ TF ▸
TFAP2A ▸ TFPI ▸ TGFA ▸ TGFB1 ▸ TGFB2 ▸ TGFB3 ▸ TGM2 ▸
TGM4 ▸ TGM7 ▸ THBD ▸ THBS1 ▸ TIMP1 ▸ TIMP2 ▸ TIMP3 ▸
TIRAP ▸ TLR1 ▸ TLR10 ▸ TLR2 ▸ TLR3 ▸ TLR4 ▸ TLR5 ▸
TLR6 ▸ TLR7 ▸ TLR8 ▸ TLR9 ▸ TNC ▸ TNFAIP6 ▸ TNFRSF11B ▸
TNFRSF1A ▸ TNFRSF1B ▸ TNFRSF8 ▸ TNFSF10 ▸ TNFSF11 ▸ TNFSF13B ▸ TNPO1 ▸
TP53 ▸ TPO ▸ TRAF1 ▸ TRAF2 ▸ TRAF3IP2 ▸ TRAF5 ▸ TRAF6 ▸
TRD ▸ TRNAI1 ▸ TRPV1 ▸ TSC22D3 ▸ TSLP ▸ TSN ▸ TTR ▸
TXN ▸ TYK2 ▸ TYR ▸ UCN ▸ UCN2 ▸ UCN3 ▸ UTP15 ▸
UTP18 ▸ UTP20 ▸ UTP23 ▸ UTP3 ▸ UTP6 ▸ VAV1 ▸ VCAM1 ▸
VCP ▸ VEGFA ▸ VHLL ▸ VIMP ▸ VIP ▸ VWF ▸ WAS ▸
WDR61 ▸ WNK1 ▸ WNT1 ▸ WNT10B ▸ WNT11 ▸ WNT16 ▸ WNT2 ▸
WNT3 ▸ WNT4 ▸ WNT5A ▸ WNT6 ▸ XBP1 ▸ XIAP ▸ XRCC1 ▸
ZBTB16 ▸ ZFP36 ▸
Data information
Please see the Gene Interactions Track Manual.