Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ CA2 ▸ TLR1 ▸ CCL2 ▸ TLR8 ▸
TLR7 ▸ IL3 ▸ RNF19A ▸ TLR6 ▸ IL15 ▸ IL5 ▸ TLR10 ▸
LTA ▸ IL33 ▸ TGFB1 ▸ IL18 ▸ F2RL1 ▸ TCF21 ▸ TCF4 ▸
NOS2 ▸ TCF19 ▸ TCF24 ▸ TCF3 ▸ TCF23 ▸ IL22 ▸ TCF25 ▸
TCF15 ▸ TCF7 ▸ CRK ▸ TCF20 ▸ TCF12 ▸ PIK3CA ▸ NFKBIA ▸
NA ▸ CSE ▸ PIK3R1 ▸ MMP9 ▸ LPA ▸ IL1RN ▸ IL32 ▸
CTR9 ▸ LEO1 ▸ WDR61 ▸ EGF ▸ CDC73 ▸ PAF1 ▸ APOB ▸
IL31 ▸ GRAP2 ▸ HGF ▸ IL11 ▸ IFNB1 ▸ IL7 ▸ S100A8 ▸
CXCR1 ▸ MMP2 ▸ ITGAM ▸ IL9 ▸ FGF2 ▸ IL25 ▸ IL20 ▸
IL21 ▸ IL19 ▸ IL16 ▸ IL27 ▸ IL34 ▸ FAS ▸ IL26 ▸
POLDIP2 ▸ IL37 ▸ IL24 ▸ INS ▸ MMP3 ▸ SAA1 ▸ NOS1 ▸
MIF ▸ EGFR ▸ AKT1 ▸ AKT2 ▸ CRP ▸ PI3 ▸ AKT3 ▸
CXCR2 ▸ ALB ▸ IKBKB ▸ CASP4 ▸ CD14 ▸ CALM3 ▸ MMP13 ▸
MMP1 ▸ NOX1 ▸ CASP3 ▸ CASP5 ▸ CASP8 ▸ CASP14 ▸ CASP9 ▸
CASP10 ▸ CASP2 ▸ F2R ▸ NOS3 ▸ CASP16 ▸ CASP7 ▸ NOX4 ▸
CASP1 ▸ CD40LG ▸ CASP6 ▸ CASP12 ▸ HMGB1 ▸ PLG ▸ NOX5 ▸
PTX3 ▸ NOX3 ▸ ITGB2 ▸ TGFB2 ▸ TNFSF10 ▸ PTK7 ▸ CHUK ▸
MYLIP ▸ LIF ▸ PTK6 ▸ MYD88 ▸ NOD1 ▸ PTK2 ▸ IGF1 ▸
SELE ▸ PRG3 ▸ PRG4 ▸ IFNA2 ▸ MAP3K7 ▸ PRG2 ▸ MUC1 ▸
PTX4 ▸ GP6 ▸ SRC ▸ MMP8 ▸ IL12B ▸ GP9 ▸ GP2 ▸
GP5 ▸ TREM1 ▸ STAT3 ▸ CXCL12 ▸ LEP ▸ ERVK-6 ▸ IKBKG ▸
SERPINE1 ▸ S100A12 ▸ IFNA4 ▸ VCAM1 ▸ PRKAR2A ▸ IFNA7 ▸ SOD3 ▸
CRH ▸ PRKAR1B ▸ MMP14 ▸ IFNA1 ▸ IFNA14 ▸ IFNA17 ▸ HDAC2 ▸
HNRNPH1 ▸ PRKAR2B ▸ PRKACB ▸ WNK1 ▸ IFNA16 ▸ PTBP1 ▸ SOD1 ▸
PTBP2 ▸ PRKAR1A ▸ IFNA5 ▸ HNRNPF ▸ IFNA6 ▸ CSF3 ▸ IFNA10 ▸
PLD2 ▸ IFNA21 ▸ IFNA13 ▸ PRKACG ▸ LTB ▸ IFNA8 ▸ IL12A ▸
MPO ▸ PAM ▸ MMP7 ▸ VIP ▸ SOD2 ▸ SETD2 ▸ HDAC1 ▸
MMP24 ▸ MMP21 ▸ MSH3 ▸ MMP12 ▸ CXCL10 ▸ EDN1 ▸ MMP10 ▸
SPP1 ▸ CAT ▸ MMP19 ▸ CCL3 ▸ MMP20 ▸ MMP11 ▸ MMP25 ▸
IL1R1 ▸ PLD1 ▸ ELANE ▸ MMP28 ▸ EGR1 ▸ MMP26 ▸ MMP15 ▸
TNFRSF1A ▸ MMP17 ▸ NOD2 ▸ MMP27 ▸ FGF1 ▸ MMP16 ▸ TGFB3 ▸
CSK ▸ PLD4 ▸ CD8A ▸ TRAF6 ▸ FASLG ▸ MAP2K1 ▸ MSH2 ▸
QRICH1 ▸ AHR ▸ MSH4 ▸ PLD5 ▸ PLD6 ▸ TAB1 ▸ ANGPT2 ▸
PLD3 ▸ SYT1 ▸ NAALADL1 ▸ CD4 ▸ QRICH2 ▸ MSH5 ▸ MSH6 ▸
SST ▸ FGF7 ▸ PLA2G1B ▸ FGF8 ▸ FGF12 ▸ PDLIM7 ▸ CXCL1 ▸
FGF6 ▸ FGF16 ▸ ITGB1 ▸ TNFSF12 ▸ FGF3 ▸ SELL ▸ LTF ▸
SAA2 ▸ TXN ▸ FGF5 ▸ FGF19 ▸ C1QA ▸ ADIPOQ ▸ HSPD1 ▸
SELP ▸ PPARG ▸ CSRP1 ▸ HDAC3 ▸ RAC1 ▸ FGF11 ▸ CD28 ▸
FGF17 ▸ FGF4 ▸ SOCS3 ▸ FGF20 ▸ FGF22 ▸ FGF23 ▸ HDAC6 ▸
HDAC5 ▸ FGF13 ▸ C1QB ▸ FGF18 ▸ FGF9 ▸ CD46 ▸ STAT1 ▸
STX2 ▸ NGF ▸ CSF1 ▸ FGF21 ▸ ETS1 ▸ P2RY6 ▸ HMOX1 ▸
CD38 ▸ FGF14 ▸ FGF10 ▸ NPS ▸ RHOA ▸ MUC16 ▸ PDGFB ▸
ANGPT1 ▸ STX1A ▸ APC ▸ MUC4 ▸ MTX1 ▸ CISH ▸ MUC7 ▸
HDAC10 ▸ MUC8 ▸ HSPB1 ▸ MUC21 ▸ CD8B ▸ ST8SIA2 ▸ HDAC8 ▸
MTOR ▸ PPARA ▸ IL2RA ▸ GPI ▸ STAT4 ▸ TNMD ▸ RBBP7 ▸
PF4 ▸ HES1 ▸ CXCR4 ▸ PRTN3 ▸ MUC13 ▸ MUC17 ▸ MUC19 ▸
SETBP1 ▸ TAT ▸ CR1 ▸ TRPV1 ▸ CD79A ▸ NAP1L4 ▸ MUC15 ▸
MUC2 ▸ CXCR3 ▸ PLA2G4A ▸ MUC6 ▸ HDAC4 ▸ MUC22 ▸ MUC12 ▸
ECM2 ▸ RBBP4 ▸ CFTR ▸ PLAU ▸ ITIH4 ▸ BCL3 ▸ TNFSF13B ▸
HDAC11 ▸ HDAC7 ▸ ANG ▸ ECM1 ▸ HDAC9 ▸ PRKCD ▸ SAA4 ▸
RHO ▸ MUC20 ▸ AGTR2 ▸ CPOX ▸ HSPG2 ▸ PDCD11 ▸ PRR21 ▸
TGFA ▸ MT3 ▸ BCL10 ▸ RELB ▸ PRR26 ▸ IBD6 ▸ PKD1 ▸
PRR22 ▸ FGA ▸ MUC5AC ▸ PRDX2 ▸ SIGLEC7 ▸ IBD7 ▸ PRKAB2 ▸
CXCL6 ▸ IBD5 ▸ APEX1 ▸ CCR5 ▸ HDC ▸ CHI3L1 ▸ UTP23 ▸
PRR15 ▸ FGG ▸ NR4A2 ▸ TAC4 ▸ SEA ▸ IBD3 ▸ MAP2K7 ▸
HES3 ▸ OSM ▸ PRR3 ▸ ICAM2 ▸ EPO ▸ ADAM17 ▸ ELF4 ▸
ICAM4 ▸ ADCYAP1 ▸ UTP15 ▸ UTP20 ▸ PRR5 ▸ PAEP ▸ CXCL17 ▸
CALM1 ▸ PRR16 ▸ PRR13 ▸ ARG1 ▸ ETS2 ▸ PGD ▸ PRR7 ▸
TP53 ▸ UTP18 ▸ IL17F ▸ MAP3K1 ▸ ELF3 ▸ IBD2 ▸ LPL ▸
CXCL9 ▸ TAC3 ▸ PRKAA1 ▸ SELPLG ▸ MET ▸ PRKCA ▸ UTP3 ▸
DEFA1 ▸ A2M ▸ MT4 ▸ TAC1 ▸ SMAD3 ▸ PGF ▸ RENBP ▸
MPL ▸ ICOSLG ▸ ADAM11 ▸ PRR14 ▸ IFI44 ▸ CALM2 ▸ EMD ▸
CXCL11 ▸ PRKAA2 ▸ ESR1 ▸ PRR12 ▸ IRAK3 ▸ FCGR1A ▸ ICAM5 ▸
HES7 ▸ UTP6 ▸ NUP43 ▸ PRR19 ▸ ICAM3 ▸ PRR9 ▸ IBD9 ▸
DDIT3 ▸ PRR24 ▸ HES6 ▸ BCL2 ▸ JAK2 ▸ DUSP1 ▸ HES4 ▸
TF ▸ FOXO3 ▸ RNASE3 ▸ PRR25 ▸ PTAFR ▸ PRR18 ▸ CYP1A1 ▸
PRKAB1 ▸ IL1R2 ▸ CTNNB1 ▸ CCL20 ▸ HBEGF ▸ PRR11 ▸ HES5 ▸
GRP ▸ IBD8 ▸ PRKAG2 ▸ TPO ▸ AZU1 ▸ ARG2 ▸ PRKAG1 ▸
NR0B1 ▸ PRL ▸ PRR4 ▸ IRAK1 ▸ ROCK2 ▸ BRAF ▸ IBD4 ▸
NTS ▸ HES2 ▸ TFPI ▸ F10 ▸ SMAD6 ▸ GRB2 ▸ PARK2 ▸
ALX3 ▸ SLPI ▸ FCER2 ▸ RAG1 ▸ FUT9 ▸ HMGB3 ▸ TACR1 ▸
FOXO1 ▸ SYK ▸ NFKBIZ ▸ IDO1 ▸ PAK3 ▸ MKNK1 ▸ VCP ▸
CGN ▸ MYO16 ▸ TRNAI1 ▸ CTSB ▸ AREG ▸ CXCL14 ▸ NPY6R ▸
BMP2 ▸ CCL5 ▸ PARK7 ▸ POU2F1 ▸ CAPN12 ▸ HRAS ▸ HLA-DRB1 ▸
MTA1 ▸ FUT5 ▸ S100A9 ▸ CAPN11 ▸ ARSA ▸ CD86 ▸ HCG15 ▸
FOXP3 ▸ FOXO4 ▸ ADM ▸ PTPN22 ▸ PROK1 ▸ CEACAM1 ▸ HCG27 ▸
WNT11 ▸ CSTA ▸ WNT4 ▸ CAPN7 ▸ HCG24 ▸ BCR ▸ TMSB4X ▸
SMAD4 ▸ SOAT1 ▸ PTPN11 ▸ F7 ▸ CXCR6 ▸ HMGB2 ▸ C3 ▸
ALX4 ▸ CD69 ▸ GSTM1 ▸ SFXN1 ▸ RAC3 ▸ MYO10 ▸ FUT7 ▸
CTSS ▸ GIP ▸ PAK7 ▸ SMAD2 ▸ SMAD9 ▸ FOXO6 ▸ GAST ▸
CX3CL1 ▸ SMAD5 ▸ PGP ▸ TNP2 ▸ MRXS5 ▸ C1orf228 ▸ HCG25 ▸
PDGFA ▸ PDCD4 ▸ DUOX1 ▸ CXCL3 ▸ CCL4 ▸ HCG16 ▸ MEPE ▸
CTGF ▸ MAPKAPK2 ▸ CNR2 ▸ CD163 ▸ ADAM19 ▸ CAPN13 ▸ IGF2 ▸
CSH1 ▸ DPM1 ▸ APOA2 ▸ SPESP1 ▸ HCG9 ▸ FGB ▸ ACKR3 ▸
BLM ▸ STAT5A ▸ MAP2K3 ▸ PAK2 ▸ HBD ▸ APOE ▸ FCGR2B ▸
HCG23 ▸ KLRB1 ▸ PAK4 ▸ WNT2 ▸ CXCL13 ▸ MAP2K2 ▸ HCG18 ▸
TBP ▸ F2RL2 ▸ RNASE2 ▸ MPG ▸ MYO19 ▸ NR4A1 ▸ HCG22 ▸
JAK1 ▸ SMAD1 ▸ PAK6 ▸ AGTR1 ▸ ELAVL1 ▸ CAPN8 ▸ MAP2K4 ▸
TNFSF11 ▸ FOSL1 ▸ CDC42 ▸ CPB2 ▸ TNPO1 ▸ GHRH ▸ BPI ▸
MBP ▸ HCG14 ▸ VASP ▸ ROCK1 ▸ FUT3 ▸ ELF5 ▸ KSR2 ▸
CD1D ▸ KRT10 ▸ IFIH1 ▸ HCG17 ▸ CXCL16 ▸ FUT2 ▸ CP ▸
MTA3 ▸ HCG26 ▸ CAPN9 ▸ DEFA1B ▸ ALOX5 ▸ CPB1 ▸ THBD ▸
ALX1 ▸ CD44 ▸ CD2 ▸ FUT8 ▸ IRS1 ▸ CD83 ▸ DPM3 ▸
OXA1L ▸ DNASE1 ▸ FUT6 ▸ MAP2K6 ▸ PITX1 ▸ TNFRSF1B ▸ FUT1 ▸
CDH5 ▸ ITGA5 ▸ VAV1 ▸ TNP1 ▸ APOA1 ▸ CAPN5 ▸ CEBPA ▸
ANPEP ▸ MAP2K5 ▸ DDX58 ▸ JAK3 ▸ PTGS1 ▸ CSH2 ▸ REL ▸
TNFRSF9 ▸ GRB14 ▸ SERPINE2 ▸ ADAM10 ▸ TEC ▸ CAPN3 ▸ TPT1 ▸
NAMPT ▸ FXYD1 ▸ DNASE2 ▸ ABL1 ▸ IL23A ▸ CAPN14 ▸ CYP1A2 ▸
RETN ▸ CEACAM6 ▸ NLRP3 ▸ BCL6 ▸ RABEPK ▸ GRB7 ▸ MEFV ▸
UCN2 ▸ NPY ▸ CAPN10 ▸ MYO6 ▸ HCG21 ▸ PAH ▸ ASIP ▸
HCG4 ▸ HCG11 ▸ CAPN6 ▸ CAPN1 ▸ FMR1 ▸ WNT1 ▸ GAL ▸
PINK1 ▸ CDH1 ▸ CYP19A1 ▸ SERPINB2 ▸ SPP2 ▸ FUT11 ▸ HCG8 ▸
KDR ▸ HIF1A ▸ WNT6 ▸ SMAD7 ▸ TRAF2 ▸ CAPN15 ▸ KLK3 ▸
CXCL5 ▸ CAPN2 ▸ TSC22D3 ▸ PAK1 ▸ WNT3 ▸ VDR ▸ DPM2 ▸
ATP8A2 ▸ FGFR2 ▸ GH1 ▸ ELF2 ▸ HCG20 ▸ NPY4R ▸ CNR1 ▸
CEBPB ▸ WNT16 ▸ MTA2 ▸ RAC2 ▸ HRH1 ▸ AR ▸ FUT10 ▸
PTHLH ▸ CXCL2 ▸ GRB10 ▸ ELF1 ▸ GRPR ▸ SCARB1 ▸ HMGB4 ▸
FUT4 ▸ CA1 ▸ LBP ▸ MTNR1A ▸ PTGER3 ▸ GRM4 ▸ TAS2R40 ▸
NPBWR2 ▸ GRM7 ▸ SSTR4 ▸ P2RY12 ▸ ADRA2A ▸ HTR1A ▸ TAS2R16 ▸
NMUR2 ▸ NMUR1 ▸ RXFP3 ▸ BDKRB1 ▸ TAS2R14 ▸ TAS2R39 ▸ CHRM4 ▸
NMU ▸ GNAT3 ▸ HCAR2 ▸ TAS2R50 ▸ GALR3 ▸ DRD4 ▸ CCR4 ▸
PYY ▸ GNG2 ▸ CCL19 ▸ ADRA2C ▸ PPBP ▸ TAS2R5 ▸ CCR10 ▸
GRM3 ▸ OPRD1 ▸ TAS2R4 ▸ TAS2R13 ▸ CCR6 ▸ HTR1E ▸ FPR1 ▸
PPY ▸ SSTR2 ▸ CCR2 ▸ CCR9 ▸ TAS2R9 ▸ TAS2R42 ▸ FPR3 ▸
ANXA1 ▸ OXER1 ▸ P2RY4 ▸ S1PR2 ▸ OPRK1 ▸ TAS2R46 ▸ MCHR1 ▸
NPB ▸ MTNR1B ▸ P2RY13 ▸ TAS2R45 ▸ HCAR1 ▸ PMCH ▸ CCL25 ▸
CCL28 ▸ ADORA3 ▸ DRD3 ▸ TAS2R19 ▸ GNB1 ▸ HTR1F ▸ SSTR1 ▸
TAS2R31 ▸ HTR1D ▸ TAS2R41 ▸ TAS2R30 ▸ HTR5A ▸ CHRM2 ▸ CX3CR1 ▸
GNAI3 ▸ CCR7 ▸ GRM8 ▸ RXFP4 ▸ KNG1 ▸ TAS2R8 ▸ DARC ▸
NPY5R ▸ U2AF1 ▸ TAS2R60 ▸ CCL16 ▸ ADRA2B ▸ MT-RNR2 ▸ CCR8 ▸
SSTR3 ▸ TAS2R10 ▸ GRM6 ▸ C3AR1 ▸ ADORA1 ▸ APLNR ▸ CCL27 ▸
GNAI1 ▸ HTR1B ▸ S1PR1 ▸ SUCNR1 ▸ HCAR3 ▸ OXGR1 ▸ HRH4 ▸
TAS2R7 ▸ TAS2R43 ▸ GNAI2 ▸ GRM2 ▸ GALR2 ▸ S1PR5 ▸ PDYN ▸
GALR1 ▸ MCHR2 ▸ BDKRB2 ▸ LPAR5 ▸ TAS2R38 ▸ GABBR2 ▸ S1PR4 ▸
CCR1 ▸ GPER1 ▸ TAS2R3 ▸ NPY2R ▸ PENK ▸ TAS2R20 ▸ PTGDR2 ▸
NPBWR1 ▸ OPRL1 ▸ DRD2 ▸ SSTR5 ▸ HEBP1 ▸ NPY1R ▸ S1PR3 ▸
INSL5 ▸ HRH3 ▸ TAS2R1 ▸ XCR1 ▸ C5AR1 ▸ GABBR1 ▸ PNOC ▸
Data information
Please see the Gene Interactions Track Manual.