Gene interactions and pathways from curated databases and text-mining
INS: top 25 interacting genes (chr11:2181008-2182439)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only INS-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-INS interactions     Show top Genes on graph    

Less-frequently mentioned interactions with INS, not among the Top 25
Other genes interacting with INS. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M AACS AANAT ABCA1 ABCA4 ABCC8 ABCG1
ABL1 ACACA ACAD8 ACAN ACD ACE ACHE
ACLY ACP1 ACP2 ACP5 ACP6 ACPP ACSL1
ACSS2 ACTB ADA ADCY1 ADCY10 ADCY2 ADCY3
ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1
ADD1 ADH4 ADH5 ADH6 ADH7 ADIPOQ ADIPOR1
ADIPOR2 ADK ADM ADRB3 AFP AGRP AGT
AGTR1 AGTR2 AGXT AHR AHSA1 AHSG AIF1
AIRE AKR1C3 AKT1S1 ALAS1 ALB ALPI ALX3
ANG ANGPT2 ANGPTL4 ANXA1 ANXA6 AOC3 APLN
APOA1 APOA4 APOA5 APOB APOC3 APOE APOM
APP APPL1 AQP2 AQP3 AQP7 AQP9 ARC
ARF1 ARF3 ARF4 ARF5 ARF6 ARG1 ARG2
ARHGEF7 ARNT ARPC1B ARSA ARSE ATF2 ATF3
ATF4 ATF6 ATM ATP11A ATP2A3 ATP5O AVP
AWAT2 BAAT BAD BATF2 BAX BCL10 BCL2
BCL3 BCL5 BCL6 BCL9 BDNF BGLAP BLM
BLVRB BMP3 BPNT1 BRAF BRS3 C1QBP C9orf3
CA1 CA2 CA3 CABP1 CABP2 CABP4 CABP5
CABP7 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1G
CALB1 CALCA CALM1 CALM2 CALM3 CAMK1 CAMK4
CANX CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14
CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8
CAPN9 CASP1 CASP10 CASP12 CASP14 CASP16 CASP2
CASP3 CASP4 CASP5 CASP6 CASP7 CASP8 CASP9
CASR CAT CAV1 CAV2 CAV3 CBFA2T2 CBL
CCK CCL2 CCNC CCND1 CCND2 CCNG1 CD2
CD36 CD38 CD40LG CD46 CD55 CDC42 CDC73
CDK4 CDK5 CDK8 CDKN1A CDKN1B CEBPA CEBPB
CEBPD CEBPZ CENPK CETP CFD CGA CHAT
CHGA CHGB CHKA CHUK CIC CIDEA CIDEC
CISH CLN3 CLU CNP CNR1 COA1 COA3
COA4 COA5 COA6 COL4A5 COMT COQ2 COQ3
COQ4 COQ5 COQ6 COQ7 COQ9 CORT CPA1
CPB2 CPE CPLX1 CPLX3 CPLX4 CPOX CPP
CPT1A CPT2 CPZ CRAT CREB1 CREB3 CREB5
CREM CRH CRK CRP CRTC2 CRYAB CS
CSF1R CSF2 CSH2 CSN2 CSN3 CSRP1 CTF1
CTNNB1 CTR9 CTSB CTSD CTSE CUL1 CXADR
CXCL1 CXCL11 CXCL12 CXCL3 CYP19A1 CYP2B6 CYP2E1
CYP3A CYP51A1 CYP7A1 DBH DBI DDIT3 DDIT4
DES DGAT1 DGKA DIANPH DIO1 DIO2 DIO3
DLG4 DLL1 DLL4 DNAJB9 DNM1 DNM2 DNM3
DOC2A DOC2B DOK1 DOK2 DOK3 DOK4 DOK5
DOK6 DOK7 DPH1 DPH2 DPH3 DPH5 DPH6
DPH7 DPP10 DPP3 DPP4 DPP6 DPP7 DPP8
DPP9 DSG1 DST DUSP1 ECI1 ECM1 ECM2
EDN1 EDN2 EDN3 EDNRA EEF1A2 EEF2K EGF
EGFR EGR1 EGR2 EHMT1 EIF2AK2 EIF2S1 EIF4E
EIF4EBP1 EIF4G1 EIF4G2 EIF4G3 ELK1 ELL2 ELL3
ENSA EPAS1 EPCAM EPHA3 EPHB2 EPO EPS15
EPS8 EPX ERBB3 ERF ERG ERO1L ERVK-6
ESR1 ESR2 F8 FABP2 FABP3 FABP4 FADS1
FADS2 FAM3B FAS FASN FAT1 FAU FBP1
FBP2 FBXO32 FFAR1 FFAR3 FFAR4 FGB FGF1
FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17
FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23
FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9
FGFR1 FGFR2 FGFR3 FGFR4 FLNC FLT1 FLT4
FN1 FNTA FOS FOSL1 FOXA1 FOXA2 FOXC2
FOXO1 FOXO3 FOXO4 FOXO6 FSHMD1A FST FUT1
FUT10 FUT11 FUT2 FUT3 FUT4 FUT5 FUT6
FUT7 FUT8 FUT9 FXR1 FXR2 FXYD1 G6PC
G6PC2 G6PC3 G6PD GABRA1 GABRB2 GABRG2 GAD1
GAD2 GAL GALNT2 GAPDH GAST GC GCK
GCLC GDI2 GDNF GH1 GHR GHRH GHSR
GIP GIT1 GIT2 GJA1 GJD2 GK GLI1
GLIS3 GLP1R GLRX GLUD1 GLUD2 GNB2L1 GNRH1
GNRH2 GOT2 GP2 GP5 GP6 GP9 GPC4
GPD1 GPD2 GPER1 GPI GPLD1 GPR1 GPR101
GPR107 GPR108 GPR110 GPR111 GPR112 GPR113 GPR114
GPR115 GPR116 GPR119 GPR12 GPR123 GPR124 GPR125
GPR126 GPR128 GPR132 GPR133 GPR135 GPR137 GPR139
GPR141 GPR142 GPR143 GPR144 GPR146 GPR148 GPR149
GPR15 GPR150 GPR151 GPR152 GPR153 GPR155 GPR156
GPR157 GPR158 GPR160 GPR161 GPR162 GPR17 GPR171
GPR173 GPR174 GPR176 GPR179 GPR18 GPR180 GPR182
GPR183 GPR19 GPR20 GPR21 GPR22 GPR25 GPR26
GPR27 GPR3 GPR31 GPR32 GPR33 GPR34 GPR35
GPR36 GPR37 GPR39 GPR4 GPR42 GPR45 GPR50
GPR52 GPR55 GPR56 GPR6 GPR61 GPR62 GPR63
GPR64 GPR65 GPR68 GPR75 GPR78 GPR79 GPR82
GPR83 GPR84 GPR85 GPR87 GPR88 GPR97 GPR98
GPRC6A GPX1 GPX2 GPX3 GPX4 GPX5 GPX6
GPX7 GPX8 GRAP2 GRB10 GRB14 GRB2 GRK1
GRK4 GRK5 GRK6 GRK7 GRP GSK3A GSK3B
GYG1 GYS1 GYS2 H6PD HADH HAO1 HBA1
HBB HCL1 HCL2 HCL3 HDAC1 HDAC2 HGF
HHEX HIF1A HK1 HK2 HK3 HLA-B HLA-DQA1
HLA-DQA2 HLA-DQB1 HLA-DRB1 HMGA1 HMGB1 HMGCR HMOX1
HNF1A HNF1B HNF4A HNRNPF HNRNPK HNRNPU HOXA3
HOXA5 HOXA9 HPGDS HRAS HSD11B1 HSD11B2 HSP90AA1
HSP90AB1 HSPA5 HSPB3 HSPD1 HSPG2 HTR2C HYOU1
IAPP IARS ICAM1 IDE IFI44 IFIT3 IFNB1
IFNG IGF1 IGF1R IGF2 IGF2R IGFBP1 IGFBP2
IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IKBKB IL10
IL11 IL12A IL12B IL13 IL15 IL16 IL18
IL19 IL1A IL1B IL1RN IL2 IL20 IL21
IL22 IL24 IL25 IL26 IL27 IL3 IL31
IL32 IL33 IL34 IL37 IL4 IL5 IL6
IL7 IL8 IL9 ILK INHBA INPP5D INPPL1
INSIG1 INSIG2 INSM1 INSR INSRR INTS2 IRF1
IRF6 IRS2 IRS4 ISL1 JAK1 JAK2 JAK3
JUN KCNH4 KCNJ4 KCNMA1 KCNQ1 KHDRBS1 KIR3DL1
KISS1 KIT KITLG KL KLF11 KLF15 KLF3
KLF7 KLK3 KLKB1 KMT2A KNG1 KNTC1 KSR1
LAMB1 LCN2 LCT LDHA LDLR LEO1 LEP
LEPR LGALS1 LIMK1 LIPC LIPE LIPG LNPEP
LPA LPIN2 LPL LRP1 LRP2 LRP5 LTB
LYPLA1 LYPLA2 M6PR MAFA MAFB MALT1 MAP2
MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7
MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15
MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MAPKAP1
MARCKS MATN1 MBP MCAT MCOLN1 MDM2 ME1
ME2 ME3 MED1 MED10 MED12 MED13 MED14
MED15 MED16 MED17 MED21 MED23 MED24 MED25
MED26 MED27 MED31 MED4 MED6 MED7 MED8
MEPE MET MFN2 MICE MIF MLN MLST8
MLXIPL MMP1 MMP12 MMP13 MMP14 MMP2 MMP9
MOK MPI MPO MRE11A MRXS5 MS MSC
MSH2 MSH3 MSH4 MSH5 MSH6 MSI1 MSI2
MSTN MT2A MT3 MT4 MTOR MTTP MTX1
MYC MYH1 MYH10 MYH11 MYH13 MYH14 MYH15
MYH16 MYH2 MYH3 MYH4 MYH6 MYH7 MYH8
MYH9 MYLIP MYLK MYO10 MYO16 MYO19 MYO6
MYOG NA NACA NAMPT NCF1 NCK1 NCK2
NCL NCOA6 NEUROD1 NEUROD2 NEUROD4 NEUROD6 NEUROG3
NFKB1 NFKBIA NGDN NGF NGFR NIDDM1 NIDDM2
NKX2-1 NKX2-2 NLGN2 NMB NMU NNAT NNT
NOD1 NOD2 NOS1 NOS2 NOS3 NOV NOX1
NOX3 NOX4 NOX5 NPPA NPS NPW NPY
NPY2R NPY4R NPY6R NR1I3 NR2F2 NR3C1 NR4A1
NR4A3 NR5A1 NTS NUP43 NUTF2 OAS1 OAS2
OAS3 ODC1 OGT OMG OPN1LW OPRM1 OTC
P2RY1 P2RY2 P2RY6 P4HB PAEP PAF1 PAK1
PAK2 PAK3 PAK4 PAK6 PAK7 PAPPA PARP1
PARP10 PARP11 PARP12 PARP14 PARP15 PARP16 PARP2
PARP3 PARP4 PARP6 PARP8 PARP9 PASK PAX4
PAX6 PC PCK1 PCK2 PCNA PCSK1 PCSK9
PDC PDCD11 PDE3A PDE3B PDGFRA PDGFRB PDHA1
PDHX PDK1 PDK2 PDK4 PDP1 PDPK1 PDX1
PEA15 PFKFB3 PGC PGD PGF PGR PHB
PHLPP1 PIK3C2A PIK3C3 PIK3CA PIK3CB PIK3CG PIK3R1
PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIKFYVE PIP PITX2
PKD1 PKD2 PKD3 PKN1 PKN2 PKN3 PLA2G15
PLA2G1B PLA2G4A PLAT PLAU PLCG1 PLD1 PLD2
PLD3 PLD4 PLD5 PLD6 PLG PLIN1 PLIN2
PLN PLP1 PLTP PMEL PMS1 PMS2 PNP
PNPLA2 PNPLA3 POLDIP2 POMC POR POT1 PPARA
PPARD PPARG PPARGC1A PPARGC1B PPAT PPP1CC PPP1R12A
PPP1R3A PPP2CA PPP2R1A PPP2R2B PPP3R1 PPY PREB
PRG2 PRG3 PRG4 PRKAA1 PRKAA2 PRKAB1 PRKAB2
PRKACB PRKACG PRKAG1 PRKAG2 PRKAR1A PRKAR1B PRKAR2A
PRKAR2B PRKCA PRKCB PRKCD PRKCG PRKCZ PRL
PRLH PRM1 PRM2 PRM3 PRR5 PRSS27 PTBP1
PTBP2 PTEN PTGS2 PTH PTHLH PTK2 PTK6
PTK7 PTPN1 PTPN11 PTPN2 PTPN6 PTPRF PTS
PTTG1 PTTG2 PTX3 PTX4 PYY QRICH1 QRICH2
RAB10 RAB11A RAB12 RAB13 RAB14 RAB15 RAB17
RAB18 RAB19 RAB20 RAB21 RAB23 RAB24 RAB25
RAB26 RAB28 RAB30 RAB31 RAB32 RAB34 RAB35
RAB36 RAB37 RAB38 RAB3A RAB41 RAB42 RAB43
RAB44 RAB4A RAB5A RAC1 RAC2 RAC3 RAD50
RAF1 RALA RAPGEF4 RARB RASA1 RASA3 RB1
RBBP4 RBBP7 RBL2 RBP4 REG1A RELA REN
RENBP RETN RGN RHEB RHO RHOA RICTOR
RNF19A RPF1 RPF2 RPS10 RPS11 RPS12 RPS13
RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19
RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26
RPS27 RPS27A RPS28 RPS29 RPS3 RPS3A RPS4X
RPS4Y1 RPS5 RPS6 RPS6KA2 RPS6KA3 RPS6KA6 RPS6KB1
RPS6KB2 RPS7 RPS8 RPS9 RPSA RPTOR RYR1
RYR2 RYR3 S100A12 S11 S12 S7 SAT1
SCARB1 SCD SCP2 SCT SDC1 SEC61B SELP
SEPP1 SERPINA12 SERPINA6 SERPINB3 SERPINE1 SETD2 SFTPA1
SFTPA2 SGK1 SH2B1 SH2B2 SH2B3 SHBG SHC1
SIK2 SIRT1 SIRT3 SIRT4 SIRT6 SKP1 SLC12A3
SLC25A1 SLC25A3 SLC27A1 SLC2A1 SLC2A12 SLC2A2 SLC2A3
SLC30A7 SLC30A8 SLC5A1 SLC9A1 SLC9A3 SLCO6A1 SLPI
SMAD2 SMAD3 SMC2 SMC3 SMC4 SMC5 SMC6
SNAP25 SOAT1 SOCS1 SOCS2 SOCS3 SOCS6 SOD1
SOD2 SOD3 SORBS1 SOS1 SOS2 SOX6 SP1
SPAG8 SPARC SPHK1 SRC SREBF1 SRGN SST
SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 ST3GAL4 STAR
STAT1 STAT3 STAT5A STAT5B STH STK10 STK11
STK16 STK19 STK24 STK25 STK3 STK31 STK33
STK35 STK36 STK38 STK39 STK4 STK40 STS
STX1A STX2 STX3 STX4 STXBP1 SULF2 SYN1
SYN2 SYP SYT1 SYT10 SYT11 SYT12 SYT13
SYT14 SYT15 SYT16 SYT17 SYT2 SYT3 SYT4
SYT5 SYT6 SYT7 SYT8 SYT9 SYTL4 TAC1
TAC3 TAC4 TAPBP TAS2R13 TAT TBC1D1 TBC1D12
TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D19 TBC1D2
TBC1D20 TBC1D21 TBC1D23 TBC1D24 TBC1D25 TBC1D26 TBC1D27
TBC1D28 TBC1D29 TBC1D3 TBC1D30 TBC1D31 TBC1D32 TBC1D4
TBC1D5 TBC1D7 TBC1D8 TBC1D9 TCF12 TCF15 TCF19
TCF20 TCF21 TCF23 TCF24 TCF25 TCF3 TCF4
TCF7 TCF7L2 TEK TERF1 TERF2 TERF2IP TF
TFAP2A TFP1 TFPI TFRC TG TGFA TGFB1
TGFB2 TGFB3 TGM1 TGM2 TGM3 TGM4 TGM5
TGM6 TGM7 TH THRA THRSP TIMP1 TINF2
TK1 TK2 TLR2 TLR4 TNF TNFRSF25 TNPO3
TP53 TPM1 TPM2 TPM3 TPM4 TPO TRB
TRH TRIB3 TRIM21 TRPM4 TRPM5 TRPM6 TRPV1
TRPV2 TSC1 TSC2 TSHB TSHR TUB TXLNG
TXN TXNDC17 TXNIP TYR TYRP1 UCN3 UCP1
UCP2 UCP3 UFD1L UGCG UNC13A UTP15 UTP18
UTP20 UTP23 UTP3 UTP6 UTS2 VAMP1 VAMP2
VAMP3 VAMP4 VAMP7 VCAM1 VCP VEGFA VIP
WAS WDR61 WNK1 WNT1 WNT11 WNT16 WNT2
WNT3 WNT3A WNT4 WNT6 XRCC5 XRCC6 ZFP36
ZGLP1
Data information
Please see the Gene Interactions Track Manual.