Nebigil et al., Proc Natl Acad Sci U S A 2000
(MAP Kinase Signaling System) :
Moreover, by using the specific platelet derived growth factor receptor ( PDGFR ) inhibitor AG 1296 or by overexpressing a kinase-mutant PDGFR, we show that PDGFR kinase activity is essential for 5-HT2B triggered MAPK/cyclin D1, but not cyclin E, signaling pathways
Cartel et al., Am J Physiol Lung Cell Mol Physiol 2001
(MAP Kinase Signaling System) :
These results suggest that PDGF-BB mediated activation of p42(MAPK) requires the PDGFR-beta but is independent of its tyrosine phosphorylation