Gene interactions and pathways from curated databases and text-mining
MAPK6: top 25 interacting genes (chr15:52311415-52359572)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only MAPK6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-MAPK6 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with MAPK6, not among the Top 25
Other genes interacting with MAPK6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

IL1A NGF FOS CASP2 CASP12 CASP3 CASP1
CASP5 CASP9 CASP16 CASP14 CASP7 CASP4 CASP8
CASP6 CASP10 CRK TGFB1 IL10 ANGPT2 PIK3R1
PIK3CA PI3 SRC FGF1 DUSP1 MMP9 CREB1
PRKAR1A CDKN1A PRKAR1B CREB5 PRKACG CCL2 CREB3
PRKAR2B FGF7 PRKACB PRKAR2A FGF18 FGF9 FGF5
ANG FGF23 FGF14 FGF10 FGF8 FGF4 FGF17
TLR4 CA2 FGF22 FGF12 FGF16 FGF19 MAP2K1
FGF6 FGF13 FGF3 FGF21 FGF11 FGF20 HGF
MAPK3 HMOX1 TP53 CSF2 IFNG NUP43 PDGFB
IL2 IL4 EDN1 IFI44 LEP MMP1 CALM3
BCL2 GNRH1 CXCL12 PLA2G4A ESR1 ICAM1 TLR2
MMP2 MAPK1 LPA TCF20 TCF3 TCF7 BDNF
TCF12 CCND1 TCF19 TCF15 TCF25 TCF21 TCF24
RAF1 TCF4 TCF23 STAT3 BAX CALM2 NOX4
APOB IL12B CALM1 IGF2 HSPB1 IL12A CD40
BRAF NA IL17A NOX5 NOX1 PTPN11 PRL
HRAS MMP13 IL13 NOS3 CXCL10 IL18 MAPKAPK2
MMP3 ATF2 NOX3 PCNA RAC1 PTK2 CAT
PTK6 SHC1 NOS1 VCAM1 PTH IL3 BCR
EGR1 PTK7 TLR5 IL5 STAT1 MAP3K7 PARP1
PRKAB1 CCK PRKAG2 TNFSF11 TGFB2 HIF1A TLR9
PRKAG1 PRKAA1 AGTR1 PRKAB2 PRKAA2 AVP NPY6R
ESR2 IRS1 IL33 PLA2G1B IL24 SETD2 EPO
TLR1 PPARG ERBB2 IL25 LIF MYLIP XRCC5
XRCC6 RHO TERF2IP MMP10 IL11 POT1 RAD50
CPOX TGFB3 PTX3 IL16 JAK2 FAS TAB1
MOS ANXA6 MRE11A CDC73 BMP2 PGF TERF2
TINF2 PPP2CA HBEGF ACD IL20 PTEN PPP2R1A
PPP2R2B MMP14 TERF1 EDN3 IL7 TLR10 TLR7
MMP7 PAF1 TLR6 F2RL1 SMAD3 IL32 MMP19
CTR9 CRH WDR61 TYR TLR8 LEO1 IL21
IL22 NTRK1 TLR3 ADM IL15 BMP7 IL31
PTX4 FGFR1 BMP4 UTP20 MMP26 CXCL11 UTP23
GDNF MMP20 EDN2 MMP24 MMP27 UTP6 CXCL9
RET IL19 MMP25 RENBP UTP18 MMP12 SLC22A3
IL9 IL27 CSF1 IL34 IL37 UTP15 MTOR
MMP28 MMP21 IL26 CSF3 NPPA MMP15 UTP3
MMP8 MMP17 MMP11 NTF3 MMP16 HSPG2 CUL1
GPR3 KDR MAP2K2 TAT SMAD2 PLAU PAK1
SKP1 MAP2K4 CXCL1 RUNX2 CDC42 NPY4R ELK1
FGFR3 PRKCA PLD2 GPR137 GPR98 OSM GPR6
GPR179 GPR15 GPR31 GPR110 CXCL3 GPR62 GPR4
PPARA GPR149 GPR174 GPR123 MAPKAPK5 GPR87 GPR84
GPR180 PLCG1 GPR27 CXCL6 GPR18 GPR156 MOCOS
GPR152 CTGF GPR176 GPR82 CXCL13 GPR34 CXCL5
GPR114 FASLG GPR141 GPR146 TRAF6 GPR112 GPR64
GPR39 HRG GPR97 SERPINE1 RHOA GPR153 GPR128
GPR20 CXCL2 GPR101 GPR111 GPR161 GPR182 GPR183
GPR78 GPR83 GPR35 GPR144 CXCL16 GPR126 GPR22
SPP1 GPR19 GPR125 GPR85 GPR68 GPR17 GPR79
GPR124 GPR133 CXCL17 GPR143 GPR63 GPR158 GPR151
GPR52 GPR171 GPR116 GPR132 GPR32 GPR142 GPR88
GPR157 CXCL14 GPR42 GPR1 GPR33 GPR148 GJA1
GPR119 GPR139 GPR55 CD79A GPR75 GPR115 GPR150
GPR160 GPR26 GRB2 SYK TRH GPR21 GPR155
STAT5A GPR108 GPR162 GPR25 GPR107 GPR50 CD79B
GPR56 GPR65 GPR12 GPR61 GPR37 GPR135 GPR36
GPR45 GNRH2 GPR173 GPR113 NFKBIA SLCO6A1 ABL1
MAP2K6 ADCYAP1 SST CD44 SMAD5 SMAD7 SMAD1
BCL10 PLD1 NEUROD6 ARSK NEUROD2 CCL3 NPY
GPI CAV1 NEUROD1 EIF4E NEUROD4 VDR BMP6
NOTCH1 CDH1 CXCR4 DDIT3 CNTF S100A12 EIF2AK2
PXN SMAD4 TXN IKBKB FGFR2 CHUK RAC2
BCL6 ROCK1 NOTCH4 KRAS HNF1B MIF PEBP1
NOTCH2 ALB CNR1 JAK3 MAP2K3 SOS1 PDGFA
TNFRSF1A JAK1 PLD6 PLG BMP3 PLD5 F2R
NOTCH3 ADAM17 ILK PLD3 RAC3 MEFV SOS2
IFI27 SP1 PLD4 TIMP1 BMP15 AGTR2 ATF1
IRF1 ANGPT1 YWHAB WNT4 CYP19A1 LTA CX3CL1
TPO CDK1 MET ATP5O EPHA2 MSK32 WNT1
GAB1 CCL20 RETN ATF3 MITF BCL9 CAV3
S100A8 CAV2 BMP1 SOCS3 ITIH4 MOK PTBP1
MSK9 ARG2 MSK10 WNT6 GAST TXNIP ETS1
NCF1 ROCK2 UCN ITGA5 MAP2K7 WNT3 BSG
MSK38 WNT2 MAP2K5 VWF GIP SMAD6 ERBB3
NTF4 ATF4 SFTPC GP2 CD55 BMP10 VIP
CEBPB LDLR ANXA1 BMP5 ARG1 HNRNPF SMN1
WNT16 MIP DUSP6 GP6 GP5 GP9 GRP
WNT11 RPTOR ITGAM SYT1 GNRHR HMGB1 MAPKAPK3
SMAD9 P2RX7 GHRH ITGB1 BCL5 RASA1 BCL3
STAT6 NOD1 IFNB1 OPRM1 ADCY3 PAK2 GH1
RASGRF1 SMC5 PTPN1 MSH6 CTNNB1 ATF6 ADCY8
IRAK4 CD38 RPS27 SOAT1 ATF5 GAS6 FRS2
TMED7 RIPK2 HTR1A GSK3B IKBKG ADCY10 ITGB2
CDH2 NRG1 INSR FGFR4 SCARB1 PTHLH ADCY1
ADCY9 LTF APP PTTG1 PLCG2 SULT1E1 IL23A
MLST8 ADCY2 SMC2 PAM IGF1R NR4A1 LANCL1
ECM2 ETS2 TNPO1 PGR TIMP2 PTBP2 CR1
MUC1 KITLG ADCY5 SMC4 WNK1 CDO1 SLC9A1
MED1 MST1 GATA4 PTPN6 ADCY7 RASGRF2 APOE
CCL11 HNRNPH1 ATF7 MYD88 SMC3 ODC1 SGK1
SELL SAA1 OCLN LRPAP1 GFAP ADCY6 SMC6
ADCY4 ECM1 CIITA SIRPA CAPN2 PHKA2 IGFBP3
CEP135 GRK5 FYN CFLAR CEP76 EMD SOX9
IRAK2 APC DDR1 FST FOSL1 PPP5C P2RY2
GLI1 PLAUR SLC2A4 IL17RD VEGFC S100B IRAK1
MAP3K3 TRAF3 CD69 CCR7 MCL1 CXCR2 RB1
ZAP70 CD40LG PRTN3 DUSP10 PKD2 UTS2 GDF15
PPARD CYP24A1 HABP2 GRK7 MYC MSH2 ADORA1
ELAVL1 IDO1 MUC5B CEP97 MUC2 TGFBR2 CEP112
DIANPH GRB10 MUC16 CEP55 HLA-DRB1 MAP3K1 PAK6
CEP78 NPY2R TGFA NTRK3 GRK4 DUSP3 MSH3
ERVK-6 HDAC1 CEP41 JUNB SELE CEP68 EHMT1
CEP44 LYN CEP85 CD36 CSK CEP120 MSH5
PAK4 SOD1 SREBF1 SFN CEP152 CUL5 RABEPK
HDAC2 CD28 CEP350 LTB CBL HSP90AA1 GRK1
PLAT REG1A CTNNBL1 NPS TAS2R38 CEP104 FCER2
NTS SLC25A3 CEP164 CEP128 IRAK3 CEP192 CDK4
CEP72 GRK6 CHI3L1 OLR1 NRAS EFNA1 ZFP36
PRKCD GNA12 DUSP9 PAK7 PDLIM7 IL2RB MYLK
CEP63 GJC1 SYN1 DUSP5 GJC3 KSR1 DUSP4
MSH4 CDH5 GAB2 CSRP1 CHKA MAP3K8 EPHB1
INPPL1 CEP57 DST CRP MC1R PLCB3 SOD3
CEP95 CEP89 CD2 TIE1 PAK3 GPER1 CEP170
FBXO32 SIRT1 MBP NCF2 IL1RN PIK3CG SHH
CEP250 AKT1S1 PTK2B SELP MNAT1 CEP19 SNAP25
CEP70 DOK1 GJC2 TRAF2 WAS AR CDK2
HSPA5 PPP3R1 CEP290 CXADR SCNN1A NAMPT PRKCB
MUC5AC EPX PTH1R CLU MUC13 EYA3 RBBP4
ADAM11 DUSP23 PARP14 CDC16 MYH6 ANGPTL1 EPHA7
VCP NRG3 SMG1 CDC23 MED4 MT4 MADD
MED17 TAF9 SMPD3 PARP4 CDH12 AQP1 CYP2E1
NRG2 PIGR HDAC3 MYH13 HNRNPK PAEP NFATC1
NODAL PLCB2 EGR2 SLC33A1 ADORA3 DDT CFTR
CDH7 FAM83B TRAF7 CCL24 NR2C2 CDH10 PDK1
RBBP7 MYH3 CDH8 DNM1 SDS KCNH8 MUC8
PPP3CA CAPN14 PRDX2 ERBB2IP EFNB3 MED13 PAX6
MYH14 SOCS1 NPB CCR2 RGS4 CCL17 TRAF4
DUSP12 AIRE DUSP15 TAC3 PRDX6 PARP11 MAFA
CPA1 DUSP2 PARP12 AANAT IL17D PDGFRB AREG
ALOX5 PARP3 TNFRSF11B NF2 DRG2 MAP3K13 RBL2
AKTIP DUSP16 DYNLRB1 NEU1 ZGLP1 SYN3 RASGRP1
KLF5 CHGA ANGPT4 PRKCE IGFBP1 MYH16 MUC19
NAALADL1 A2M DUSP8 ESAT ATR CYP3A IHH
DISC1 RIT1 RAD51 MIPEP TRAF5 DAB2 CEBPA
TFRC CDK8 HCL2 GATA3 XIAP CDC26 LGALS1
CAPN10 PPP3CC TNFSF12 EGR4 CDH20 EPHA8 QRICH2
CANX MYH1 YME1L1 MUC7 PDCD11 TAF6 ARHGEF1
STAR PAN2 CAPN5 CASC3 MUC21 XCL1 CDH4
CSNK2B EIF4EBP1 CAPN7 PTCH1 P2RX4 CAPN8 TAC1
CPE GDF5 PROK1 RGS3 CDH11 DOK5 CLDN18
CDC37 CDH22 SPRY2 CAPN11 CAPN13 FUT4 MDM2
CCNB1 LOX APPL1 DUSP13 NCAM1 FLNA MRXS5
PARP10 NRP1 CDH23 MYH9 MYH4 SLPI RBL1
CISH MYL9 SERPINF1 SERPINC1 PLCB1 MED14 BAD
DUSP19 FLT3 TAB2 MYH10 C1orf228 PARP6 PTPN22
MAP3K11 DUSP28 TAC4 PTS CAPN6 PARP2 PRX
CD4 PPP3CB HSPD1 CDH3 CXCR1 CAPN12 EDNRA
MUC22 TWIST1 IGFBP5 EZR SRF MUC15 ARSA
MST1R CADM1 CCNC PPARGC1A NTRK2 CAPN9 CAPN3
FCGR2B IL6ST VAV1 TRO HRH1 MAP3K12 GHR
EYA2 IL17F TRADD MYH8 MYH11 EPHA5 CDH15
EYA4 LIFR KMT2D TSC22D3 SLC12A3 DUSP7 ADRBK1
PGD TIMP3 MATK CEBPD DUSP26 SP3 NRG4
MYH2 FOSL2 CDH19 EPHA6 CDH24 EPHA1 EPHA4
CD46 RPS6KA1 MUC6 CDC27 SPHK1 LRPPRC AGO2
TPH1 PSEN1 BTRC CAPN15 TNFSF10 MAP3K4 CDC20
MAP3K2 CDH17 CNR2 MED12 PIK3C3 CSF1R PRKD1
FSHB S100A9 CSE CDH9 SPARC DUSP11 MYH7
DUSP18 ADAMTS4 SPRED1 CCR5 PIM1 CTNND1 CDH26
PCK2 NF1 CDH18 ERBB4 CCL4 SYN2 TANK
NPR3 GAL SMURF1 GHSR CDH16 DUSP22 KCNH4
ERCC1 HTR2A PARP8 TRAF1 PSIP1 ANXA5 AQP2
PARP16 PIK3R4 MUC20 LRP1 MAP3K10 NCAM2 TGFBR1
CDC6 CDH13 BGN MED6 SRPK1 PTGES DUSP27
CD24 SPAG8 PLXNB1 CA1 PARP15 RPS6KB1 PLCB4
PAN3 PTTG2 MAP3K14 CD86 RRAS LCK EPHA10
DES MED24 EPHA3 TNFRSF9 ABCC1 MUC12 EDNRB
CAPN1 MAP3K5 NEU3 MYH15 DRG1 QRICH1 ABCB1
DISC2 MPZ HCL3 HSD11B2 PSMG1 GATA1 CCL5
HCL1 GAPDH BID KANK2 RARA MEF2C EYA1
TAF1 GNA13 MUC17 CX3CR1 CDH6 DUSP21 AJUBA
ST3GAL4 DOK4 SOD2 ITGAV ASIP BANF1 MED21
SRY MUC4 PARP9 UCP1 DUSP14 ITGB3BP ACTG1
SLC20A1 DKC1 CBFB GPX1 NAT9 PHGDH CUL2
SEPT3 TCEB1 PSMA7 SPRR2D ARHGDIA RRP7A PLEKHM1
MON1A SPG7 KNSTRN GORASP1 BAG6 PTPN5 RGS19
WDR26 COPS6 UBA52 CCND3 APOA1BP DBN1 RAB2A
ITSN1 PHACTR3 AMBRA1 PLSCR1 MTG2 ZNF600 GNAI2
EIF2S3 RPS6KA3 HNRNPH3 CRELD2 ZNF331 DDOST OSTF1
XPO1 ANK3 IDH3B WFS1 DCAF11 TDP2 DPPA4
PDCD6IP ZNF205 PHC2 ZNF133 METTL2A NUDT5 STX7
CNTN1 SNW1 MYOZ3 CNTRL EIF3C HNRNPD RPS6KA2
EIF1 MAGED1 DSCR3 CYTH2 PDLIM1 EIF4A1 TCEB2
ZNF579 PPP1R7 GNAI3 DCTN2 NOL4 SLC41A3 MGAT1
PIH1D1 RAP1GAP ZNF775 C21orf59 HAUS2 PPBP DGKZ
HACL1 CERS1 ATP5J PSAT1 NCOR1 PRPF38A RNF7
HSP90B1 C19orf80 SUSD4 SPTAN1 FXYD3 SEPT5 BBS10
SEPP1 KDSR KLC1 HERC2 PVRL2 RPS6KA6 ARPC3
MASP1 APBA2 ATG9A MBOAT7 TBL1XR1 PTPMT1 HNRNPA0
MZB1 MYBL2 MBIP CSE1L FOXO3 GNAI1 WWC1
EDF1 NRXN2 RRAD ACTR1B GLRX3 UBE2L3 NEURL4
NDUFS6 TPI1 DNAJC28 FAM49B RAB31 SERPINA4 FBXL16
URB1 NELFB UBC SNAPC4 HIP1 CCT3 TUBA1A
METTL17 ZNF671 GNB2L1 UBE3A TTK EEF1A2 BARX1
RPL10 ELOF1 WDR34 GALNT7 SRSF5 RPS6KA5 HSP90AB1
CA12 THAP4 MCM3 EEF1D RPS6KA4 DNAJB2
Data information
Please see the Gene Interactions Track Manual.